The association between BMI and risk of endometriosis-a meta-analysis

被引：0
作者：
Zhu, Qian [1 ]
Chen, Ya
Chen, Zexin [2 ]
机构：
[1] Zhejiang Univ, Sch Med, Affiliated Hosp 2, Dept Sci & Educ, Hangzhou 310003, Zhejiang, Peoples R China
[2] Zhejiang Univ, Sch Med, Affiliated Hosp 2, Dept Clin Epidemiol & Biostat, Hangzhou 310003, Zhejiang, Peoples R China
来源：
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE | 2016年 / 9卷 / 02期
关键词：
BMI; endometriosis; meta-analysis; HR (Hazard Ratio); OR (Oddis Ratio); BODY-MASS INDEX; PERITONEAL-FLUID; NURSES HEALTH; LEPTIN LEVELS; WOMEN; OBESITY; SIZE; DEEP;
D O I：
暂无
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Objective: The objective of this meta-analysis was to systematically assess the association between BMI and endometriosis. Methods: Relevant studies were identified through searching PubMed, Embase and Cochrane databases before August 2014. A random-effects model was derived to composite the pooled HR or OR. Results: 13 articles included in the final meta-analysis. When considering BMI as a continuous variable, pooled analysis indicated the risk of endometriosis was inversely associated with BMI (OR=0.95, 95% CI: 0.92-0.98), but a significant heterogeneity was observed. When excluded one study with HR, the heterogeneity of pooled OR decreased. When considering BMI as a category variable, the pooled analysis presented an OR of 0.61 (95% CI 0.44 to 0.85). In subgroup with a BMI cutoff value from 21 to 23, the heterogeneity decreased to 0.0%. Conclusion: Our subgroup analysis indicated that the risk of endometriosis seems to be inversely associated with BMI. But the precise relationship needs further verification research in the future.
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收藏
页码：588 / 595
页数：8
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