Rare case of hepatocellular carcinoma metastasising to the pituitary and cavernous sinus causing panhypopituitarism and bilateral ophthalmoplegia

被引：5

作者：

Ambalavanan, Jayachidambaram ^{[1
]}

Peravali, Monica ^{[2
]}

Perry, David J. ^{[2
]}

机构：

[1] MedStar Washington Hosp Ctr, Internal Med, Washington, DC 20010 USA

[2] MedStar Washington Hosp Ctr, Hematol & Oncol, Washington, DC USA

来源：

BMJ CASE REPORTS | 2020年 / 13卷 / 10期

关键词：

hepatic cancer; pituitary disorders; ophthalmology; neuroimaging; DIAGNOSIS; TUMORS; GLAND;

D O I：

10.1136/bcr-2020-236377

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Pituitary metastases, especially from a primary hepatocellular carcinoma (HCC), are rare. Review of the literature revealed only few cases reporting pituitary metastases complicated by panhypopituitarism from HCC. Calvarial metastases from HCC are even more rare. Here, we present a unique case of primary HCC with metastases to both the calvarium and the pituitary causing panhypopituitarism and bilateral ophthalmoplegia, respectively. To our knowledge, this is the first reported case of two unique and rare complications from metastatic HCC.

引用

页数：4

共 19 条

[11] Tumors metastatic to the pituitary gland: Case report and literature review [J].

Komninos, J ;

Vlassopoulou, V ;

Protopapa, D ;

Korfias, S ;

Kontogeorgos, G ;

Sakas, DE ;

Thalassinos, NC .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2004, 89 (02) :574-580

[12]

Larocca G., 2017, EDIZIONI MINERVA MED, P213

[13] Clival Metastasis of Hepatocellular Carcinoma with an Initial Histopathological Diagnosis of Atypical Pituitary Adenoma [J].

Mishima, Hiroyuki ;

Ayabe, Junichi ;

Watanabe, Masahide ;

Togin, Sota ;

Tsuchiya, Yuusuke ;

Kawasaki, Taisuke ;

Noda, Naoyuki ;

Maruyama, Takumi ;

Tanaka, Yoshihide .

JOURNAL OF NEUROLOGICAL SURGERY REPORTS, 2019, 80 (01) :E18-E22

[14] Symptomatic pituitary metastases [J].

Morita, A ;

Meyer, FB ;

Laws, ER .

JOURNAL OF NEUROSURGERY, 1998, 89 (01) :69-73

[15] Psychosis in Secondary Empty Sella Syndrome following a Russell's Viper Bite [J].

Ratnakaran, Badr ;

Punnoose, Varghese P. ;

Das, Soumitra ;

Kartha, Arjun .

INDIAN JOURNAL OF PSYCHOLOGICAL MEDICINE, 2016, 38 (03) :254-256

[16] METASTASES TO THE PITUITARY HYPOTHALAMIC AXIS - AN MR STUDY OF 7 SYMPTOMATIC PATIENTS [J].

SCHUBIGER, O ;

HALLER, D .

NEURORADIOLOGY, 1992, 34 (02) :131-134

[17]

Shah Nihar, 2015, J Nat Sci Biol Med, V6, P471, DOI 10.4103/0976-9668.160045

[18] Hepatocellular carcinoma metastasis to the brain mimicking primary pituitary tumor around the sella turcica [J].

Tamura T. ;

Kawamura Y. ;

Ikeda K. ;

Seko Y. ;

Fukushima T. ;

Kumada H. ;

Yamada S. ;

Matumaru Y. .

Clinical Journal of Gastroenterology, 2013, 6 (4) :319-325

[19] Pituitary metastasis of hepatocellular carcinoma presenting with panhypopituitarism: a case report [J].

Tanaka, Tomoko ;

Hiramatsu, Katsushi ;

Nosaka, Takuto ;

Saito, Yasushi ;

Naito, Tatsushi ;

Takahashi, Kazuto ;

Ofuji, Kazuya ;

Matsuda, Hidetaka ;

Ohtani, Masahiro ;

Nemoto, Tomoyuki ;

Suto, Hiroyuki ;

Yamamoto, Tatsuya ;

Kimura, Hirohiko ;

Nakamoto, Yasunari .

BMC CANCER, 2015, 15

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