Successful benralizumab for eosinophilic myocarditis in eosinophilic granulomatosis with polyangiitis

被引：6

作者：

Belfeki, N. ^{[1
]}

Abroug, S. ^{[1
]}

Ghriss, N. ^{[1
]}

Chouchane, I ^{[2
]}

Hamrouni, S. ^{[1
]}

Strazzulla, A. ^{[1
]}

Zayet, S. ^{[3
]}

机构：

[1] Grp Hosp Sud Ile France, Dept Internal Med, F-77000 Melun, France

[2] Grp Hosp Sud Ile France, Dept Radiol, Melun, France

[3] Nord Franche Comte Hosp, Dept Infect Dis, F-90400 Trevenans, France

来源：

CLINICAL AND EXPERIMENTAL RHEUMATOLOGY | 2022年 / 40卷 / 04期

关键词：

eosinophilic granulomatosis with polyangiitis (EGPA); myocarditis; eosinophilia; rituximab; benralizumab; CARDIAC INVOLVEMENT; AMERICAN-COLLEGE; MEPOLIZUMAB; RITUXIMAB;

D O I：

10.55563/clinexprheumatol/ahyqld

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Eosinophilic granulomatosis with polyangiitis (EGPA) is characterised by many features, including asthma, allergic rhinitis, peripheral and tissue eosinophilia, and vasculitis. Its pathophysiology is still unclear and we suggest that there are different phenotypes of EGPA, which may respond differently to available treatments. Within the most promising targeting biotherapy, benralizumab, an anti-interleukin-5 receptor alpha monoclonal antibody, has proved both highly effective and safe. We report herewith a case of EGPA presenting a myocarditis relapse successfully treated with benralizumab.

引用

页码：834 / 837

页数：4

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