Exosomes derived from TRAIL-engineered mesenchymal stem cells with effective anti-tumor activity in a mouse melanoma model

被引:70
作者
Shamili, Fazileh Hosseini [1 ]
Bayegi, Houshang Rafatpanah [1 ,2 ]
Salmasi, Zahra [3 ]
Sadri, Kayvan [4 ]
Mahmoudi, Mahmoud [1 ,5 ]
Kalantari, Mahmoudreza [6 ]
Ramezani, Mohammad [7 ,8 ]
Abnous, Khalil [7 ,9 ]
机构
[1] Mashhad Univ Med Sci, Fac Med, Dept Immunol, Mashhad, Iran
[2] Mashhad Univ Med Sci, Immunol Res Ctr, Inflammat & Inflammatory Dis Div, Mashhad, Iran
[3] Mashhad Univ Med Sci, Pharmaceut Technol Inst, Nanotechnol Res Ctr, Mashhad, Iran
[4] Mashhad Univ Med Sci, Nucl Med Res Ctr, Mashhad, Iran
[5] Mashhad Univ Med Sci, Immunol Res Ctr, Mashhad, Iran
[6] Mashhad Univ Med Sci, Ghaem Hosp, Fac Med, Dept Pathol, Mashhad, Iran
[7] Mashhad Univ Med Sci, Pharmaceut Technol Inst, Pharmaceut Res Ctr, Mashhad, Iran
[8] Mashhad Univ Med Sci, Sch Pharm, Dept Pharmaceut Biotechnol, Mashhad, Iran
[9] Mashhad Univ Med Sci, Sch Pharm, Dept Med Chem, Mashhad, Iran
关键词
IN-VITRO; EXTRACELLULAR VESICLES; STROMAL CELLS; CANCER-CELLS; TUMOR-GROWTH; APOPTOSIS; LIGAND; DELIVERY; MICROVESICLES; RESISTANCE;
D O I
10.1016/j.ijpharm.2018.07.067
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
[No abstract available]
引用
收藏
页码:218 / 229
页数:12
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