International Society of Urological Pathology (ISUP) grading of prostate cancer - An ISUP consensus on contemporary grading

被引：165
作者：
Egevad, Lars [1 ,2 ]
Delahunt, Brett [3 ]
Srigley, John R. [4 ]
Samaratunga, Hemamali [5 ,6 ]
机构：
[1] Karolinska Inst, Dept Pathol & Oncol, Stockholm, Sweden
[2] Karolinska Univ Hosp, Dept Pathol, Stockholm, Sweden
[3] Univ Otago, Dept Pathol & Mol Med, Wellington Sch Med & Hlth Sci, Wellington, New Zealand
[4] McMaster Univ, Dept Pathol & Mol Med, Hamilton, ON, Canada
[5] Aquesta Pathol, Brisbane, Qld, Australia
[6] Univ Queensland, Sch Med, Brisbane, Qld, Australia
来源：
APMIS | 2016年 / 124卷 / 06期
关键词：
Prostate cancer; grading; ISUP grade; Gleason grade; PROGNOSTIC-SIGNIFICANCE; GLEASON; CARCINOMA; PROGRESSION; SYSTEM;
D O I：
10.1111/apm.12533
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The International Society of Urological Pathology (ISUP) has issued guidelines for the grading of prostate cancer based on a consensus conference held in 2014. The recommendations resulting from the 2014 consensus conference were a further development of 2005 ISUP modified Gleason grading. In the 2014 system, morphological criteria are clarified, including updated definitions of Gleason pattern 4. In addition to the continued reporting of Gleason scores, we also recommend that Gleason scores 6, 3+4=7, 4+3=7, 8 and 9-10, respectively, be reported as five groups, i.e. ISUP grades 1-5. This new grading system has the dual benefit of predicting patient outcome as well as facilitating patient communication.
引用
收藏
页码：433 / 435
页数：3
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