Diagnostic Pitfalls in Immunology Testing

被引:3
作者
Maher, Lewena [1 ]
Perugino, Cory [2 ,3 ]
机构
[1] Beth Israel Lahey Hlth, Internal Med, Burlington, MA USA
[2] Massachusetts Gen Hosp, Div Rheumatol Allergy & Immunol, Boston, MA 02114 USA
[3] MIT & Harvard, Ragon Inst MGH, 400 Technol Sq, Cambridge, MA 02139 USA
关键词
Autoantibody; Rheumatoid factor; ANA; ANCA; Antiphospholipid; IgG4; CYCLIC CITRULLINATED PEPTIDE; IGA RHEUMATOID FACTORS; ANTIPHOSPHOLIPID SYNDROME; CLASSIFICATION CRITERIA; ANTINUCLEAR ANTIBODIES; CONSENSUS STATEMENT; PROZONE PHENOMENON; DISEASE-ACTIVITY; AUTOANTIBODIES; ARTHRITIS;
D O I
10.1016/j.cll.2019.07.005
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
Immunology testing is relevant for the diagnosis of many autoimmune conditions. However, diagnostic pitfalls arise owing to incorrect interpretation of results and incomplete understanding of the underlying technique or immune-mediated condition. Here, we review the diagnostic considerations related to commonly used immunology tests. Specifically, we summarize the caveats pertinent to the interpretation of rheumatoid factor, antinuclear antibodies, antiphospholipid antibodies, antineutrophil cytoplasmic antibodies, and serum IgG4 testing.
引用
收藏
页码:567 / +
页数:13
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