New monoterpene glucosides from Dracocephalum komarovi and their anti-inflammatory activity

被引：7
作者：
Toshmatov, Zokir O. [1 ,2 ,3 ]
Li, Jun [1 ,2 ]
Eshbakova, Komila A. [4 ]
Tang, Dan [1 ,2 ]
Xin, Xuelei [1 ,2 ]
Aisa, Haji Akber [1 ,2 ]
机构：
[1] Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Plant Resources & Chem Arid Zone, Urumqi 830011, Peoples R China
[2] Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, State Key Lab Basis Xinjiang Indigenous Med Plant, Urumqi 830011, Peoples R China
[3] Univ Chinese Acad Sci, Beijing 100039, Peoples R China
[4] Acad Sci Uzbek, Inst Chem Plant Subst, Tashkent 100170, Uzbekistan
来源：
PHYTOCHEMISTRY LETTERS | 2019年 / 33卷
关键词：
Dracocephalum komarovi; Monoterpene glucosides; Anti-inflammatory activity; NO production; CONSTITUENTS; GLYCOSIDES;
D O I：
10.1016/j.phytol.2019.08.005
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Three new monoterpene glycosides, komarovins A-C (1-3), together with one known monoterpene glycoside (4) and two known phenolic compounds (5-6), were isolated and identified from the aerial parts of Dracocephalum komarovi. Their structures were established based on comprehensive spectroscopic data analysis and comparison with reported data. Compounds 2-4 were investigated for their inhibition against nitric oxide (NO) production in LPS-stimulated RAW264.7 macrophages, and all of them displayed inhibitory effects on NO production.
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页码：102 / 105
页数：4
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