Recent developments in asymmetric transfer hydrogenation with Hantzsch esters: A biomimetic approach

被引：274

作者：

You, Shu-Li ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organomet Chem, Shanghai 200032, Peoples R China

来源：

CHEMISTRY-AN ASIAN JOURNAL | 2007年 / 2卷 / 07期

关键词：

asymmetric catalysis; Hantzsch esters; hydrogenation; organocatalysis; reductive amination;

D O I：

10.1002/asia.200700081

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

By utilizing Hantzsch esters as the hydrogen sources asymmetric transfer hydrogenation of C=C, C=N, and C=O is realized in the presence of an organocatalyst or a metal-ligand complex, thus affording versatile chiral building blocks in high yields with excellent enantioselectivities under mild conditions. A detailed discussion of recent findings and an assessment of this biomimetic approach are presented in this review.

引用

页码：820 / 827

页数：8

共 81 条

[1] Organocatalytic hydride transfers: A new concept in asymmetric hydrogenations [J].