A rare debilitating neurological adverse effect of ranolazine due to drug interaction with clarithromycin

被引:7
|
作者
Mishra, Ajay [1 ]
Pandya, Himanshu V. [1 ]
Dave, Nikhil [1 ]
Mathew, Mahesh [1 ]
Sapre, Chinmaye M. [1 ]
Chaudhary, Sneha [1 ]
机构
[1] Pramukhswami Med Coll, Dept Med, Karamsad, Gujarat, India
关键词
Drug interaction; medication error; neurological adverse effects; ranolazine; CHRONIC ANGINA; ATENOLOL;
D O I
10.4103/0253-7613.140593
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Medication errors may occur at any point during patient care in the health care system. Drug interaction in known with macrolide antibiotics and ranolazine and is primarily related to effects on the cytochrome P4503A (CYP3A) metabolic pathway. This case highlights medication errors that resulted in rare debilitating neurological adverse effects of ranolazine in an elderly due to drug interaction with clarithromycin.
引用
收藏
页码:547 / 548
页数:2
相关论文
共 27 条
  • [21] Effect of the Clopidogrel-Proton Pump Inhibitor Drug Interaction on Adverse Cardiovascular Events in Patients with Acute Coronary Syndrome
    Bhurke, Sharvari M.
    Martin, Bradley C.
    Li, Chenghui
    Franks, Amy M.
    Bursac, Zoran
    Said, Qayyim
    PHARMACOTHERAPY, 2012, 32 (09): : 809 - 818
  • [22] Dynamic Effect of β-Lactam Antibiotic Inactivation Due to the Inter- and Intraspecies Interaction of Drug-Resistant Microbes
    Jeong, Yoon
    Ahmad, Saeed
    Irudayaraj, Joseph
    ACS BIOMATERIALS SCIENCE & ENGINEERING, 2024, 10 (03) : 1461 - 1472
  • [23] Clozapine-Related Functional Bowel Obstruction: A Rare Adverse Effect Unmasking Quetiapine and Benztropine Interaction Raising Need for Bowel Surveillance
    Tiwari, Apoorv
    Kambhatla, Swathi
    George, Nathan
    Anumolu, Prathyusha
    Malik, Nikhale
    Kambhatla, Sujata
    ACG CASE REPORTS JOURNAL, 2024, 11 (05)
  • [24] A retrospective study of the effect of modified multi-drug therapy in Nepali leprosy patients following the development of adverse effects due to dapsone
    Sapkota, Bishwa Raj
    Shrestha, Kanchha
    Pandey, Bijay
    Walker, Stephen L.
    LEPROSY REVIEW, 2008, 79 (04) : 425 - 428
  • [25] First Sequencing of Caprine Mdr1 (Abcb1) mRNA Due to Suspected Neurological Adverse Drug Reaction in a Thuringian Goat Following Extra-Label Use of Doramectin
    Nuernberger, Daniela
    Mueller, Simon F.
    Hamann, Melanie
    Geyer, Joachim
    FRONTIERS IN VETERINARY SCIENCE, 2021, 8
  • [26] Excessive Hypocoagulation in Therapy with Warfarin within Polypharmacy: Using online database Multi-Drug Interaction Checker and Graphic "Time-Effect-Drug Administration" to Eliminate Adverse Drug Event (Case Report)
    Krasnov, Gleb S.
    Kazancev, Igor, V
    RATIONAL PHARMACOTHERAPY IN CARDIOLOGY, 2018, 14 (05) : 687 - 690
  • [27] Effect of Clarithromycin, a Strong CYP3A and P-glycoprotein Inhibitor, on the Pharmacokinetics of Edoxaban in Healthy Volunteers and the Evaluation of the Drug Interaction with Other Oral Factor Xa Inhibitors by a Microdose Cocktail Approach
    Lenard, Alexander
    Hermann, Simon A. A.
    Stoll, Felicitas
    Burhenne, Juergen
    Foerster, Kathrin I. I.
    Mikus, Gerd
    Meid, Andreas D.
    Haefeli, Walter E. E.
    Blank, Antje
    CARDIOVASCULAR DRUGS AND THERAPY, 2024, 38 (04) : 747 - 756