Potential protective effects of thiamine supplementation on the ruminal epithelium damage during subacute ruminal acidosis

被引：17

作者：

Ma, Jian ^{[1
]}

Shah, Ali Mujtaba ^{[1
]}

Wang, Zhisheng ^{[1
]}

Fan, Xue ^{[2
]}

机构：

[1] Sichuan Agr Univ, Anim Nutr Inst, Low Carbon Breeding Cattle & Safety Prod Univ Key, Chengdu 611130, Peoples R China

[2] Xinjiang Agr Univ, Coll Anim Sci, Urumqi, Peoples R China

来源：

ANIMAL SCIENCE JOURNAL | 2021年 / 92卷 / 01期

基金：

中国国家自然科学基金;

关键词：

inflammatory response; ruminal epithelium; subacute ruminal acidosis; thiamine; tight junction; NF-KAPPA-B; GROWTH-FACTOR-I; HIGH-GRAIN DIET; DAIRY-COWS; RUMEN EPITHELIUM; BARRIER FUNCTION; SHEEP RUMEN; SHORT COMMUNICATION; TIGHT JUNCTIONS; L-ARGININE;

D O I：

10.1111/asj.13579

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

In ruminants, the ruminal epithelium not only has the function of absorbing nutrients but also is an important tissue to prevent harmful substances in the rumen from entering the blood circulation. Thus, the normal function of ruminal epithelium is critical for ruminants. However, subacute ruminal acidosis induced by high-concentrate diets often damages the barrier function of ruminal epithelium in ruminants. Recently, many studies have shown that dietary supplementation with thiamine is an effective method to alleviate subacute ruminal acidosis. In order to provide theoretical reference for the in-depth study of subacute ruminal acidosis and the application of thiamine in the future, this review introduces the effects of subacute ruminal acidosis on morphological structure, inflammatory response, and tight junction of ruminal epithelium. In addition, this paper summarizes the role of thiamine in maintaining ruminal epithelial function of ruminants during subacute ruminal acidosis challenge.

引用

页数：9

共 71 条

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