Successful co-administration of dabigatran etexilate and protease inhibitors ritonavir/lopinavir in a patient with atrial fibrillation

被引：13

作者：

Barco, Stefano ^{[1
,2
]}

Coppens, Michiel ^{[1
]}

van den Dool, Erik-Jan ^{[3
]}

van de Kerkhof, Daan ^{[4
]}

Stroobants, An K. ^{[3
]}

Middeldorp, Saskia ^{[1
]}

机构：

[1] Univ Amsterdam, Acad Med Ctr, Dept Vasc Med, NL-1105 AZ Amsterdam, Netherlands

[2] Univ Pavia, Dept Internal Med, IRCCS Policlin San Matteo Fdn, I-27100 Pavia, Italy

[3] Univ Amsterdam, Acad Med Ctr, Lab Gen Clin Chem, NL-1105 AZ Amsterdam, Netherlands

[4] Catharina Hosp, Clin Lab, Eindhoven, Netherlands

来源：

THROMBOSIS AND HAEMOSTASIS | 2014年 / 112卷 / 04期

关键词：

IDENTIFICATION; WARFARIN;

D O I：

10.1160/TH14-03-0214

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：836 / 838

页数：3

共 9 条

[1]

Boehringer Ingelheim Pharmaceuticals I, 2014, HIGHL PRESCR INF, P1

[2]

Boehringer-Ingelheim, 2012, PRAD PROD MON, P1

[3] Rapid identification of P-glycoprotein substrates and inhibitors [J].

Chang, Cheng ;

Bahadduri, Praveen M. ;

Polli, James E. ;

Swaan, Peter W. ;

Ekins, Sean .

DRUG METABOLISM AND DISPOSITION, 2006, 34 (12) :1976-1984

[4] Dabigatran versus Warfarin in Patients with Atrial Fibrillation. [J].

Connolly, Stuart J. ;

Ezekowitz, Michael D. ;

Yusuf, Salim ;

Eikelboom, John ;

Oldgren, Jonas ;

Parekh, Amit ;

Pogue, Janice ;

Reilly, Paul A. ;

Themeles, Ellison ;

Varrone, Jeanne ;

Wang, Susan ;

Alings, Marco ;

Xavier, Denis ;

Zhu, Jun ;

Diaz, Rafael ;

Lewis, Basil S. ;

Darius, Harald ;

Diener, Hans-Christoph ;

Joyner, Campbell D. ;

Wallentin, Lars .

NEW ENGLAND JOURNAL OF MEDICINE, 2009, 361 (12) :1139-1151

[5]

EMA, PRAD SUMM PROD CHAR, P1

[6] Oral bioavailability of dabigatran etexilate (Pradaxa®) after co-medication with verapamil in healthy subjects [J].

Haertter, Sebastian ;

Sennewald, Regina ;

Nehmiz, Gerhard ;

Reilly, Paul .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2013, 75 (04) :1053-1062

[7] Dabigatran Etexilate in Atrial Fibrillation Patients With Severe Renal Impairment: Dose Identification Using Pharmacokinetic Modeling and Simulation [J].

Lehr, Thorsten ;

Haertter, Sebastian ;

Liesenfeld, Karl-Heinz ;

Staab, Alexander ;

Clemens, Andreas ;

Reilly, Paul A. ;

Friedman, Jeffrey .

JOURNAL OF CLINICAL PHARMACOLOGY, 2012, 52 (09) :1373-1378

[8] Safety and efficacy of dabigatran versus warfarin in patients undergoing catheter ablation of atrial fibrillation: a systematic review and meta-analysis [J].

Providencia, Rui ;

Albenque, Jean-Paul ;

Combes, Stephane ;

Bouzeman, Abdeslam ;

Casteigt, Benjamin ;

Combes, Nicolas ;

Narayanan, Kumar ;

Marijon, Eloi ;

Boveda, Serge .

HEART, 2014, 100 (04) :324-335

[9] The Effect of Dabigatran Plasma Concentrations and Patient Characteristics on the Frequency of Ischemic Stroke and Major Bleeding in Atrial Fibrillation Patients The RE-LY Trial (Randomized Evaluation of Long-Term Anticoagulation Therapy) [J].

Reilly, Paul A. ;

Lehr, Thorsten ;

Haertter, Sebastian ;

Connolly, Stuart J. ;

Yusuf, Salim ;

Eikelboom, John W. ;

Ezekowitz, Michael D. ;

Nehmiz, Gerhard ;

Wang, Susan ;

Wallentin, Lars .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2014, 63 (04) :321-328

← 1 →