Overview of SARS-CoV-2 infection in adults living with HIV

被引:3
作者
Ambrosioni, Juan [1 ]
Blanco, Jose Luis [1 ]
Reyes-Uruena, Juliana M. [3 ,4 ]
Davies, Mary-Ann [5 ]
Sued, Omar [6 ]
Marcos, Maria Angeles [2 ]
Martinez, Esteban [1 ]
Bertagnolio, Silvia [7 ,8 ]
Alcami, Jose [1 ,9 ]
Miro, Jose M. [1 ]
机构
[1] Univ Barcelona, Infect Dis Serv, Hosp Clin IDIBAPS, Barcelona 08036, Spain
[2] Univ Barcelona, Microbiol Serv, Hosp Clin ISGlobal, Barcelona, Spain
[3] Agencia Salut Publ Catalunya, Ctr Estudis Epidemiol Infecc Transmiss Sexual & S, Barcelona, Spain
[4] CIBER Epidemiol & Salud Publ CIBERESP, Madrid, Spain
[5] Univ Cape Town, Sch Publ Hlth & Family Med, Ctr Infect Dis Epidemiol & Res, Cape Town, South Africa
[6] Fdn Huesped, Buenos Aires, DF, Argentina
[7] WHO, Dept Global HIV Hepatitis & STI Programmes, Geneva, Switzerland
[8] UCL, Dept Infect & Populat Hlth, London, England
[9] Inst Salud Carlos III, AIDS Immunopathogenesis Unit, Madrid, Spain
关键词
CORONAVIRUS DISEASE 2019; RISK-FACTORS; COVID-19; PEOPLE; OUTCOMES; INTERFERONS; VACCINATION; INDUCTION; RESPONSES; LOCKDOWN;
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Around 2-5 million deaths and more than 110 million COVID-19 cases have been reported globally. Although it initially appeared that HIV infection was not a risk factor for COVID-19 or more severe disease, more recent large studies suggest that people living with HIV (particularly with low CD4 cell counts or untreated HIV infection) might have a more severe clinical course than those who are HIV-negative. Moreover, the COVID-19 pandemic has disrupted HIV prevention and treatment services worldwide, creating huge challenges to the continuity of essential activities. We have reviewed the most relevant features of COVID-19 in people living with HIV and highlighted topics where further research is required.
引用
收藏
页码:e294 / e305
页数:12
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