The effect of dihydropyrimidine dehydrogenase (DPD) activity and germline thymidylate synthase (TS) gene polymorphisms on the survival of colorectal cancer patients treated by adjuvant 5-fluorouracil

被引：0
作者：
Kralovanszky, J.
Budai, B.
Pandi, E.
Hitre, E.
Adleff, V.
Katona, C.
Reti, A.
Komlosi, V.
Orosz, Z.
Lang, I.
机构：
[1] Natl Inst Oncol, Budapest, Hungary
[2] Uzsoki Hosp, Oncoradiol Ctr, Budapest, Hungary
来源：
EJC SUPPLEMENTS | 2005年 / 3卷 / 02期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：187 / 187
页数：1
相关论文
共 50 条
[31]   Putative role of dihydropyrimidine dehydrogenase in the toxic side effect of 5-fluorouracil in colorectal cancer patients [J].
Katona, C ;
Kralovanszky, J ;
Rosta, A ;
Pandi, E ;
Fonyad, G ;
Toth, K ;
Jeney, A .
ONCOLOGY, 1998, 55 (05) :468-474
[32]   Changes in intratumoral thymidylate synthase (TS) and dihydropyrimidine dehydrogenase (DPD) mRNA expression in colorectal and gastric cancer during continuous tegafur infusion [J].
Uchida, K ;
Hayashi, K ;
Kuramochi, H ;
Takasaki, K .
INTERNATIONAL JOURNAL OF ONCOLOGY, 2001, 19 (02) :341-346
[33]   Relationships between the expression of thymidylate synthase, dihydropyrimidine dehydrogenase, and orotate phosphoribosyltransferase and cell proliferative activity and 5-fluorouracil sensitivity in colorectal carcinoma [J].
R. Fujii ;
A. Seshimo ;
S. Kameoka .
International Journal of Clinical Oncology, 2003, 8 (2) :72-78
[34]   Thymidylate synthase (TS) and P53 as prognostic factors for patients (PTS) with colorectal cancer (CA) treated with adjuvant 5-fluorouracil (5FU) and levamisol (LEV) [J].
VanTriest, B ;
Pinedo, HM ;
Zoetmulder, FAN ;
Loftus, BM ;
Telleman, F ;
Schoenmakers, PS ;
VanGroeningen, CJ ;
Peters, GJ .
EUROPEAN JOURNAL OF CANCER, 1997, 33 :764-764
[35]   Thymidylate synthase and dihydropyrimidine dehydrogenase are related to histological effects of 5-fluorouracil and cisplatin neoadjuvant chemotherapy for primary gastric cancer patients [J].
Fukuda, H ;
Takiguchi, N ;
Koda, K ;
Oda, K ;
Seike, K ;
Miyazaki, M .
CANCER INVESTIGATION, 2006, 24 (03) :235-241
[36]   Thymidylate synthase polymorphism in Mexican patients with colon cancer treated with 5-fluorouracil [J].
Patricia Rios-Ibarra, Clara ;
Janeth Rodriguez-Silva, Claudia ;
Alonso Lopez-Chuken, Yamil ;
Ortiz-Lopez, Rocio ;
Fernandez-Castillo, Elisa ;
Del Toro Runzer, Claudia Beatriz ;
Paul Armenta-Perez, Vicente ;
Pablo Flores-Gutierrez, Juan ;
Quintanilla-Guzman, Arturo ;
Salinas-Santander, Mauricio ;
Francisco Gonzalez-Guerrero, Juan ;
Bosques-Padilla, Francisco ;
Santos, Arturo ;
Guadalupe Martinez-Rodriguez, Herminia .
JOURNAL OF BUON, 2016, 21 (04) :935-940
[37]   Associations between thymidylate synthase polymorphisms and survival in patients with colorectal cancer treated with 5-FU-based adjuvant chemotherapy [J].
Chang, Shih ;
Sung, Fung ;
Hsieh, Ling ;
Tang, Rei ;
Yeh, Chih .
CANCER RESEARCH, 2009, 69
[38]   Predictive significance of thymidylate synthase and dihydrapyrimidine dehydrogenase levels in patients with completely resected colorectal cancer receiving adjuvant 5-fluorouracil therapy. [J].
Jense, SA ;
Vainer, B ;
Sorensen, JB .
JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (16) :278S-278S
[39]   Prognostic role of thymidylate synthase (TS) gene polymorphisms in gastric cancer patients treated with surgery and adjuvant chemotherapy. [J].
Kawakami, K ;
Graziano, F ;
Watanabe, G ;
Ruzzo, A ;
Santini, D ;
Catalano, V ;
Bisonni, R ;
Ficarelli, R ;
Cascinu, S ;
Magnani, M .
JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (16) :318S-318S
[40]   Low Dihydropyrimidine Dehydrogenase Correlates with Prolonged Survival in Patients with Lung Adenocarcinoma Treated with 5-Fluorouracil [J].
Shintani, Yasushi ;
Inoue, Masayoshi ;
Funakoshi, Yasunobu ;
Matsumura, Akihide ;
Ohta, Mitsunori ;
Maeda, Hajime ;
Okumura, Meinoshin .
ANTICANCER RESEARCH, 2011, 31 (12) :4665-4671
12345