The effect of dihydropyrimidine dehydrogenase (DPD) activity and germline thymidylate synthase (TS) gene polymorphisms on the survival of colorectal cancer patients treated by adjuvant 5-fluorouracil

被引：0
作者：
Kralovanszky, J.
Budai, B.
Pandi, E.
Hitre, E.
Adleff, V.
Katona, C.
Reti, A.
Komlosi, V.
Orosz, Z.
Lang, I.
机构：
[1] Natl Inst Oncol, Budapest, Hungary
[2] Uzsoki Hosp, Oncoradiol Ctr, Budapest, Hungary
来源：
EJC SUPPLEMENTS | 2005年 / 3卷 / 02期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：187 / 187
页数：1
相关论文
共 50 条
[21]   A polymorphism in the enhancer region of the thymidylate synthase promoter influences the survival of colorectal cancer patients treated with 5-fluorouracil [J].
Iacopetta, B ;
Grieu, F ;
Joseph, D ;
Elsaleh, H .
BRITISH JOURNAL OF CANCER, 2001, 85 (06) :827-830
[22]   A polymorphism in the enhancer region of the thymidylate synthase promoter influences the survival of colorectal cancer patients treated with 5-fluorouracil [J].
B Iacopetta ;
F Grieu ;
D Joseph ;
H Elsaleh .
British Journal of Cancer, 2001, 85 :827-830
[23]   Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase [J].
Salonga, D ;
Danenberg, KD ;
Johnson, M ;
Metzger, R ;
Groshen, S ;
Tsao-Wei, DD ;
Lenz, HJ ;
Leichman, CG ;
Leichman, L ;
Diasio, RB ;
Danenberg, PV .
CLINICAL CANCER RESEARCH, 2000, 6 (04) :1322-1327
[24]   Thymidylate synthase (TS) gene polymorphisms affect disease free- (DFS) and overall (OS) survival of colorectal cancer (CRC) patients treated with adjuvant 5-fluorouracil-folinic acid (FUFA). [J].
Hitre, E ;
Adleff, V ;
Budai, B ;
Szabó, E ;
Horvath, Z ;
Lang, I ;
Czeglédi, F ;
Orosz, Z ;
Gazdag, A ;
Kralovanszky, J .
JOURNAL OF CLINICAL ONCOLOGY, 2004, 22 (14) :265S-265S
[25]   Thymidylate synthase expression pattern is a prognostic factor in patients with colorectal cancer treated with 5-fluorouracil [J].
Sanchez-Prudencio, S ;
Femandez-Contreras, E ;
Alcala-Zamora, T ;
Diaz, B ;
Martinez-Amores, B ;
Velasco, A ;
Gamallo, C ;
Gisbert, JP .
GASTROENTEROLOGY, 2005, 128 (04) :A161-A162
[26]   Thymidylate synthase expression pattern is a prognostic factor in patients of colorectal cancer treated with 5-fluorouracil [J].
Fernández-Contreras, ME ;
De Ayala, BJ ;
De Paredes, MLG ;
Velasco, A ;
Majano, PL ;
Palacios, J ;
Gamallo, C .
INTERNATIONAL JOURNAL OF ONCOLOGY, 2004, 25 (04) :877-885
[27]   Roles of thymidylate synthase and dihydropyrimidine dehydrogenase in tumor progression and sensitivity to 5-fluorouracil in human gastric cancer [J].
Terashima, M ;
Irinoda, T ;
Fujiwara, H ;
Nakaya, T ;
Takagane, A ;
Abe, K ;
Yonezawa, H ;
Oyama, K ;
Inaba, T ;
Saito, K ;
Takechi, T ;
Fukushima, M .
ANTICANCER RESEARCH, 2002, 22 (2A) :761-768
[28]   TS, DPD, and OPRT gene expression of colorectal cancer: Correlation with chemosensitivity to 5-fluorouracil [J].
Ishida, H ;
Ohsawa, T ;
Hayashi, Y ;
Nakada, H ;
Yokoyama, M ;
Inokuma, S ;
Shirakawa, K ;
Hashimoto, D .
DISEASES OF THE COLON & RECTUM, 2004, 47 (06) :1015-1015
[29]   Implications of thymidylate synthase gene polymorphisms, KRAS and BRAF mutations in the survival of patients with colorectal cancer treated with adjuvant chemotherapy [J].
Ntavatzikos, A. ;
Spathis, A. ;
Patapis, P. ;
Peros, G. ;
Panayiotides, I. ;
Papadopoulos, I. ;
Koumarianou, A. .
ANNALS OF ONCOLOGY, 2018, 29 :176-176
[30]   Combination of polymorphisms within 5′ and 3′ untranslated regions of thymidylate synthase gene modulates survival in 5 fluorouracil-treated colorectal cancer patients [J].
Fernandez-Contreras, Maria-Encarnacion ;
Javier Sanchez-Hernandez, Jose ;
Gonzalez, Enrique ;
Herraez, Beletn ;
Dominguez, Irene ;
Lozano, Maria ;
Garcia De Paredes, Maria-Luisa ;
Munoz, Alberto ;
Gamallo, Carlos .
INTERNATIONAL JOURNAL OF ONCOLOGY, 2009, 34 (01) :219-229
12345