Flexible Localized Surface Plasmon Resonance Sensor with Metal-Insulator-Metal Nanodisks on PDMS Substrate

被引：81

作者：

Chang, Chiao-Yun ^{[1
]}

Lin, Hsiang-Ting ^{[1
]}

Lai, Ming-Sheng ^{[1
,2
]}

Shieh, Teng-Yi ^{[1
,2
]}

Peng, Chien-Chung ^{[1
]}

Shih, Min-Hsiung ^{[1
,2
,3
]}

Tung, Yi-Chung ^{[1
]}

机构：

[1] Acad Sinica, RCAS, Taipei 11529, Taiwan

[2] Natl Chiao Tung Univ NTCU, Dept Photon, Hsinchu 30010, Taiwan

[3] NSYSU, Dept Photon, Kaohsiung 80424, Taiwan

来源：

SCIENTIFIC REPORTS | 2018年 / 8卷

关键词：

INFRARED PERFECT ABSORBER; LIGHT-ABSORPTION; WIDE-ANGLE; BROAD-BAND; SIZE; SENSITIVITY; CELLS;

D O I：

10.1038/s41598-018-30180-8

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The small sized, flexible, high-performed and bio-compatible sensing devices are the critical elements to realize the bio-related detection or on-site health monitoring systems. In this work, the flexible localized surface plasmon resonance (LSPR) bio-sensors were demonstrated by integrating the metal-insulator-metal (MIM) nanodisks with bio-compatible polydimethylsiloxane (PDMS) substrate. The different geometries of MIM nanodisk sensors were investigated and optimized to enhance the spatial overlap of the LSPR waves with the environment, which lead to a high sensitivity of 1500 nm/RIU. The omni-directional characteristics of LSPR resonances were beneficial for maintaining the device sensitivity stable under various bending curvatures. Furthermore, the flexible MIM nanodisk LSPR sensor was applied to detect A549 cancer cells in PBS+ solution. The absorption peak of the MIM-disk LSPR sensor obviously redshift to easily distinguish between the phosphate buffered saline (PBS+) solution with A549 cancer cells and without cells. Therefore, the flexible MIM nanodisk LSPR sensor is suitable to develop on-chip microfluidic biosensors for detection of cancer cells on nonplanar surfaces.

引用

页数：8

共 40 条

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