Convenient magnesiation of aromatic and heterocyclic rings bearing a hydroxy group in presence of LiCl

被引：55

作者：

Kopp, F ^{[1
]}

Krasovskiy, A ^{[1
]}

Knochel, P ^{[1
]}

机构：

[1] Univ Munich, Dept Chem, D-81377 Munich, Germany

来源：

CHEMICAL COMMUNICATIONS | 2004年 / 20期

关键词：

D O I：

10.1039/b409664a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The reaction of various iodophenols with MeMgCl in presence of LiCl followed by the addition of i-PrMgCl provides the corresponding magnesiated magnesium phenolates as THF soluble reagents; this approach can be extended to heterocyclic compounds bearing a hydroxy group like pyridines and quinolines.

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收藏

页码：2288 / 2289

页数：2

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