Anti-Muscle Specific Kinase (Anti-MuSK) Positive Myasthenia Gravis Overlapping With Parkinson's Disease: A Challenging Diagnosis

被引：6

作者：

Albassam, Mohammed S. ^{[1
]}

Thabet, Salman A. ^{[1
]}

Hmoud, Mohammed ^{[2
,3
]}

Makkawi, Seraj ^{[1
,2
,4
]}

机构：

[1] King Saud Bin Abdulaziz Univ Hlth Sci, Coll Med, Jeddah, Saudi Arabia

[2] Minist Natl Guard Hlth Affairs, Dept Med, Jeddah, Saudi Arabia

[3] Univ Bisha, Coll Med, Bisha, Saudi Arabia

[4] King Abdullah Int Med Res Ctr, Res & Dev, Jeddah, Saudi Arabia

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2021年 / 13卷 / 05期

关键词：

myasthenia gravis (mg); parkinson' s disease; adult neurology; anti-musk; rituximab; saudi arabia; EPIDEMIOLOGY;

D O I：

10.7759/cureus.14839

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The concomitance between Parkinson's disease (PD) and myasthenia gravis (MG) is rare, with only a few case reports in the literature and only one of them with positive anti-muscle specific kinase (anti-MuSK) MG. The overlap between PD and MG symptoms can cause a diagnostic dilemma for the treating physician. In this report, we present a 73-year-old lady with a history of recurrent falls, dysphagia, and diplopia. She was found to have ptosis, vertical gaze restriction, neck extension, and flexion weakness, as well as features of parkinsonism, including masked face appearance, asymmetrical limbs rigidity, and bradykinesia. She was found to have a high titer antibody for MuSK MG. Her MG symptoms were treated successfully with rituximab.

引用

页数：4

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