Ultrafast Detection of Sulfur Dioxide Derivatives by a Distinctive "Dual-Positive-Ion" Platform that Features a Doubly Activated but Irreversible Michael Addition Site

被引：18

作者：

Bao, Xiazhen ^{[1
]}

Cao, Xuehui ^{[1
]}

Yuan, Yong ^{[1
]}

Zhou, Bo ^{[2
]}

Huo, Congde ^{[1
]}

机构：

[1] Northwest Normal Univ, Coll Chem & Chem Engn, Lanzhou 730070, Gansu, Peoples R China

[2] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Gansu, Peoples R China

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 2021年 / 69卷 / 16期

基金：

中国国家自然科学基金;

关键词：

sulfur dioxide; fluorescent probe; dual-positive-ion platform; doubly activated site; reagent kit; RATIOMETRIC FLUORESCENT-PROBE; TURN-ON PROBE; SO2; DERIVATIVES; SELECTIVE DETECTION; SERUM SULFITE; BISULFITE; MITOCHONDRIA; SAMPLES; CELLS; WATER;

D O I：

10.1021/acs.jafc.1c00797

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

Sulfur dioxide (SO2) is a gaseous signaling molecule and widely used as a preservative for foods, but its excessive intake is closely related to a series of diseases. Therefore, the development of a potent fluorescence probe for the detection of SO2 in foods and biological systems is of great significance. Herein, we report for the first time a "dual-positive-ion" platform-based fluorescence probe CMQ, designed by a doubly activated but irreversible strategy, which results in its ultrafast response to SO2 within 5 s in pure aqueous solution together with a low detection limit as 15.6 nM. In addition, the probe was successfully applied for imaging of SO2 in mitochondria of living cells and zebrafish and prepared as a reagent kit for convenient and instantaneous quantification of HSO3- in real food samples.

引用

页码：4903 / 4910

页数：8