Thin films of La0.7Sr0.3MnO3 (LSMO) have been deposited by magnetron sputtering on LaAlO3 (LAO), SrTiO3 (STO), MgO, Si/Si3N4, Si/MgO and Si/YSZ substrates. Buffer layers of YSZ, MgO and Si3N4 have been obtained by magnetron sputtering or chemical vapour deposition techniques. The influence of deposition parameters, substrate temperature as well as lattice mismatch between the substrate and manganite layer on magnetoresistance of obtained films have been investigated. The magnetoresistance MR = [R(H) - R(0)]/R(0), where R(H) and R(0) is the film resistance in and without magnetic field, has been measured in in-plane and out-of-plane direction of applied magnetic field H. The polycrystalline films, especially on Si/Si3N4 substrates, exhibited significant low-field MR. The LSMO films obtained at elevated temperature on LAO or STO substrates possessed low-resistivity values and metallic resistivity up to T > 300 K, implying possible applications in tunneling structures. (C) 2000 Elsevier Science Ltd. All rights reserved.