Adenomatous Polyp With Intestinal Metaplasia of the Esophagus (Barrett Esophagus) in a Dog

被引：18

作者：

Gibson, C. J. ^{[1
]}

Parry, N. M. A. ^{[1
]}

Jakowski, R. M. ^{[1
]}

Cooper, J. ^{[2
]}

机构：

[1] Tufts Univ, Cummings Sch Vet Med, Dept Biomed Sci, Sect Pathol, North Grafton, MA 01536 USA

[2] Tufts Univ, Cummings Sch Vet Med, Dept Clin Sci, North Grafton, MA 01536 USA

来源：

VETERINARY PATHOLOGY | 2010年 / 47卷 / 01期

关键词：

adenomatous polyp; Barrett esophagus; canine; metaplasia; standard poodle; COLUMNAR METAPLASIA; ADENOCARCINOMA; CANCER; REFLUX; MODEL;

D O I：

10.1177/0300985809352973

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Multiple endoscopic biopsy specimens of esophageal mucosa were received from a 13-year-old castrated male standard Poodle. The dog was presented for painful swallowing. Endoscopically, the distal aspect of the esophagus was inflamed with a polypoid mass that protruded into the esophageal lumen. Histologically, the stratified squamous epithelium overlying the mass and lining the adjacent esophageal mucosa was replaced by papillary projections covered by columnar epithelium with goblet cells supported by a fibrous stroma. This article reports a case of spontaneous esophageal adenomatous polyp with intestinal metaplasia (Barrett esophagus) and reviews the pathogenesis of esophageal metaplasia and adenocarcinoma.

引用

页码：116 / 119

页数：4

共 15 条

[1] Molecular biology of Barrett's cancer [J].

Atherfold, Paul A. ;

Jankowski, Janusz A. .

BEST PRACTICE & RESEARCH CLINICAL GASTROENTEROLOGY, 2006, 20 (05) :813-827

[2] Histopathologic evaluation of an animal model for Barrett's esophagus and adenocarcinoma of the distal esophagus [J].

Buskens, Christianne J. ;

Huscher, Jan B. F. ;

van Gulik, Thomas M. ;

ten Kate, Fiebo J. ;

van Lanschot, J. Jan B. .

JOURNAL OF SURGICAL RESEARCH, 2006, 135 (02) :337-344

[3] EXPERIMENTAL COLUMNAR METAPLASIA IN THE CANINE ESOPHAGUS [J].

GILLEN, P ;

KEELING, P ;

BYRNE, PJ ;

WEST, AB ;

HENNESSY, TPJ .

BRITISH JOURNAL OF SURGERY, 1988, 75 (02) :113-115

[4] Reflux esophagitis in three cats associated with metaplastic columnar esophageal epithelium [J].

Gualtieri, Massimo ;

Olivero, Daniela .

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 2006, 42 (01) :65-70

[5] Neoplastic precursor lesions in Barrett's esophagus [J].

Hormick, Jason L. ;

Odze, Robert D. .

GASTROENTEROLOGY CLINICS OF NORTH AMERICA, 2007, 36 (04) :775-+

[6] Immunohistochemical study of p53, c-erbB-2, and PCNA in Barrett's esophagus with dysplasia and adenocarcinoma arising from experimental acid or alkaline reflux model [J].

Kawaura, Y ;

Tatsuzawa, Y ;

Wakabayashi, T ;

Ikeda, N ;

Matsuda, M ;

Nishihara, S .

JOURNAL OF GASTROENTEROLOGY, 2001, 36 (09) :595-600

[7] Changing role of in vivo models in columnar-lined lower esophagus [J].

Koak, Y ;

Winslet, M .

DISEASES OF THE ESOPHAGUS, 2002, 15 (04) :271-277

[8]

LI H, 1994, SURGERY, V115, P176

[9]

Liu C., 2005, Pathologic basis of disease, V7th ed., P804

[10]

Miwa Koichi, 2005, Nihon Rinsho, V63, P1387

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