Common mechanisms activate plant guard receptors and TLR4

被引：5

作者：

Kagan, Jonathan C. ^{[1
,2
]}

机构：

[1] Boston Childrens Hosp, Boston, MA 02446 USA

[2] Harvard Univ, Sch Med, Boston, MA 02446 USA

来源：

TRENDS IN IMMUNOLOGY | 2014年 / 35卷 / 10期

关键词：

ASYMPTOTE; RESPONSES;

D O I：

10.1016/j.it.2014.08.009

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In metazoans, the innate immune system uses Pattern Recognition Receptors to detect conserved microbial products, whereas in plants Guard Receptors detect virulence factors or activities encoded by pathogens. In a recent study, Williams and colleagues report that plant Guard receptors can be activated by a mechanism remarkably similar to that of mammalian Toll-like Receptor 4.

引用

页码：454 / 456

页数：3

共 10 条

[1] Plant pathogens and integrated defence responses to infection [J].

Dangl, JL ;

Jones, JDG .

NATURE, 2001, 411 (6839) :826-833

[2] Regulation of interactions of Gram-negative bacterial endotoxins with mammalian cells [J].

Gioannini, Theresa L. ;

Weiss, Jerrold P. .

IMMUNOLOGIC RESEARCH, 2007, 39 (1-3) :249-260

[3]

JANEWAY CA, 1989, COLD SH Q B, V54, P1

[4] The plant immune system [J].

Jones, Jonathan D. G. ;

Dangl, Jeffery L. .

NATURE, 2006, 444 (7117) :323-329

[5] Phosphoinositide Binding by the Toll Adaptor dMyD88 Controls Antibacterial Responses in Drosophila [J].

Marek, Lorri R. ;

Kagan, Jonathan C. .

IMMUNITY, 2012, 36 (04) :612-622

[6] Approaching the Asymptote: 20 Years Later [J].

Medzhitov, Ruslan .

IMMUNITY, 2009, 30 (06) :766-775

[7]

Meng J, 2011, SCI CHINA PHYS CHEM, V54, P187, DOI 10.1007/s11433-010-4225-5

[8] RRS1 and RPS4 provide a dual Resistance-gene system against fungal and bacterial pathogens [J].

Narusaka, Mari ;

Shirasu, Ken ;

Noutoshi, Yoshiteru ;

Kubo, Yasuyuki ;

Shiraishi, Tomonori ;

Iwabuchi, Masaki ;

Narusaka, Yoshihiro .

PLANT JOURNAL, 2009, 60 (02) :218-226

[9] Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice:: Mutations in Tlr4 gene [J].

Poltorak, A ;

He, XL ;

Smirnova, I ;

Liu, MY ;

Van Huffel, C ;

Du, X ;

Birdwell, D ;

Alejos, E ;

Silva, M ;

Galanos, C ;

Freudenberg, M ;

Ricciardi-Castagnoli, P ;

Layton, B ;

Beutler, B .

SCIENCE, 1998, 282 (5396) :2085-2088

[10] Structural Basis for Assembly and Function of a Heterodimeric Plant Immune Receptor [J].

Williams, Simon J. ;

Sohn, Kee Hoon ;

Wan, Li ;

Bernoux, Maud ;

Sarris, Panagiotis F. ;

Segonzac, Cecile ;

Ve, Thomas ;

Ma, Yan ;

Saucet, Simon B. ;

Ericsson, Daniel J. ;

Casey, Lachlan W. ;

Lonhienne, Thierry ;

Winzor, Donald J. ;

Zhang, Xiaoxiao ;

Coerdt, Anne ;

Parker, Jane E. ;

Dodds, Peter N. ;

Kobe, Bostjan ;

Jones, Jonathan D. G. .

SCIENCE, 2014, 344 (6181) :299-303

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