Two new phenolic compounds from the seeds of Machilus yunnanensis

被引：4

作者：

Long, Hui ^{[1
,2
]}

Luo, Dan ^{[1
]}

Yang, Yan ^{[1
]}

Zhang, Ling ^{[1
]}

Pu, De-Bing ^{[1
,2
]}

Li, Jie ^{[1
]}

Chen, Xue-Jiao ^{[1
]}

Zhu, Xu ^{[1
]}

Liu, Shuang ^{[1
]}

Gao, Jun-Bo ^{[1
,2
]}

Wang, Yong-Mei ^{[1
,2
]}

Ji, Xu ^{[1
]}

Xiao, Wei-Lie ^{[1
]}

机构：

[1] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China

[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2016年 / 18卷 / 10期

关键词：

Lauraceae; Machilus yunnanensis; phenolic compounds; vasorelaxant effect; GLYCOSIDES; BARK;

D O I：

10.1080/10286020.2016.1187139

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Chemical constituents investigation on the seeds of Machilus yunnanensis led to two new phenolic compounds 8-O-acetyl-phenylethanoid-4-O--D-glucopyranoside (1) and (E)-2,3-bis(4-hydroxyphenyl)acrylaldehyde (2), together with 16 known compounds. Their structures were elucidated on the basis of spectroscopic data analysis (IR, MS, 1D, and 2D NMR). Meanwhile, compounds 1-3, 6-13, 17, and 18 were evaluated for vasorelaxant effects on the rat endothelium-intact thoracic aorta rings precontracted with phenylephrine (PE) or KCl. The bioassay results showed that compound 17 had significant vasorelaxant effect on the endothelium-intact thoracic aorta rings precontracted with KCl.

引用

页码：952 / 958

页数：7

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