Systemic retinoids - What's new?

被引：20
作者：
Saurat, JH [1 ]
机构：
[1] Univ Hosp Geneva, Dept Dermatol, Geneva, Switzerland
来源：
DERMATOLOGIC CLINICS | 1998年 / 16卷 / 02期
关键词：
D O I：
10.1016/S0733-8635(05)70016-4
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Despite major advances in the molecular biology and pharmacology of retinoids, no new compound has been developed for systemic use. This article addresses some questions related to the indications of oral retinoids already on the market, e.g. isotretinoin, acitretin, as well as tretinoin, reviews some recently reported undesirable effects, and discusses the recent concepts generated by basic research that may lead to new drugs to be used in pharmacology.
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页码：331 / +
页数：11
相关论文
共 101 条
[1]   DOSE-DEPENDENT PHARMACOKINETICS OF ALL-TRANS-RETINOIC ACID [J].
ADAMSON, PC ;
BALIS, FM ;
SMITH, MA ;
MURPHY, RF ;
GODWIN, KA ;
POPLACK, DG .
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1992, 84 (17) :1332-1335
[2]   Isotretinoin-PUVA in women with psoriasis [J].
Anstey, A ;
Hawk, JLM .
BRITISH JOURNAL OF DERMATOLOGY, 1997, 136 (05) :798-799
[3]   MASSIVE ISOTRETINOIN INTOXICATION [J].
AUBIN, S ;
LORETTE, G ;
MULLER, C ;
VAILLANT, L .
CLINICAL AND EXPERIMENTAL DERMATOLOGY, 1995, 20 (04) :348-350
[4]  
BAGOT M, 1995, LANCET, V346, P376
[5]   PREVENTION OF SKIN-CANCER AND REDUCTION OF KERATOTIC SKIN-LESIONS DURING ACITRETIN THERAPY IN RENAL-TRANSPLANT RECIPIENTS - A DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY [J].
BAVINCK, JNB ;
TIEBEN, LM ;
VANDERWOUDE, FJ ;
TEGZESS, AM ;
HERMANS, J ;
TERSCHEGGET, J ;
VERMEER, BJ .
JOURNAL OF CLINICAL ONCOLOGY, 1995, 13 (08) :1933-1938
[6]   Etretinate may work where acitretin fails [J].
Bleiker, TO ;
Bourke, JF ;
GrahamBrown, RAC ;
Hutchinson, PE .
BRITISH JOURNAL OF DERMATOLOGY, 1997, 136 (03) :368-370
[7]  
BLUM A, 1995, ACTA DERM-VENEREOL, V75, P332
[8]   Acitretin therapy is effective for psoriasis associated with human immunodeficiency virus infection [J].
Buccheri, L ;
Katchen, BR ;
Karter, AJ ;
Cohen, SR .
ARCHIVES OF DERMATOLOGY, 1997, 133 (06) :711-715
[9]   2 NUCLEAR SIGNALING PATHWAYS FOR VITAMIN-D [J].
CARLBERG, C ;
BENDIK, I ;
WYSS, A ;
MEIER, E ;
STURZENBECKER, LJ ;
GRIPPO, JF ;
HUNZIKER, W .
NATURE, 1993, 361 (6413) :657-660
[10]  
Carlberg C, 1996, JOURNAL OF INVESTIGATIVE DERMATOLOGY SYMPOSIUM PROCEEDINGS, VOL 1, NO 1, APRIL 1996, V1, P82
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