Zn-doped etch-and-rinse model dentin adhesives: Dentin bond integrity, biocompatibility, and properties

被引:32
作者
Barcellos, Daphne Camara [1 ]
Fonseca, Beatriz Maria [2 ]
Pucci, Cesar Rogerio [3 ]
Cavalcanti, Bruno das Neves [4 ]
Persici, Erasmo De Souza [5 ]
de Paiva Goncalves, Sergio Eduardo [3 ]
机构
[1] UNESP Univ Estadual Paulista, Dept Restorat Dent, Sao Jose dos Campos Sch Dent, Sao Jose Dos Campos, SP, Brazil
[2] UNESP Univ Estadual Paulista, Inst Sci & Technol, Clin Res Acad Grp, Sao Jose Dos Campos, SP, Brazil
[3] UNESP Univ Estadual Paulista, Dept Restorat Dent, Sao Jose Dos Campos, SP, Brazil
[4] Univ Michigan, Sch Dent, Dept Cariol Restorat Sci & Endodont, Ann Arbor, MI 48109 USA
[5] Embraer Def & Secur, Elect Syst, Sao Jose Dos Campos, Brazil
关键词
Dental adhesive; Dentin-bond agents; Zinc oxide; Methacrylates; Matrix metalloproteinase inhibitors; Collagen; MECHANICAL-PROPERTIES; CLINICAL-PERFORMANCE; COLLAGEN DEGRADATION; ZINC-OXIDE; IN-VITRO; ACID; CYTOTOXICITY; CONTRACTION; STRENGTH; SYSTEMS;
D O I
10.1016/j.dental.2016.04.003
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Objective. This study assessed a 6 month resin/dentin bond's durability and cytotoxic effect of Zn-doped model dentin adhesives. The mechanical and physicochemical properties were also tested. Methods. A model etch-and-rinse single-bottle adhesive was formulated (55 wt.% Bis-GMA, 45 wt.% HEMA, 0.5 wt.% CQ 0.5 wt.% DMAEMA) and Zinc methacrylate (Zn-Mt) or ZnO nanoparticles (ZnOn) were added to the model's adhesive, resulting in three groups: Group Control (control model adhesive); Group Zn-Mt (1 wt.% Zn-Mt incorporated to adhesive) and Group ZnOn (1 wt.% ZnOn incorporated to adhesive). The microtensile bond strength (mTBS) was assessed after 24 h or 6 months in water storage. Mechanical properties (diametral tensile strength/DTS, flexural strength/FS, flexural modulus/FM, resilience modulus/RM, and compressive strength/CS) and physicochemical properties (polymerization shrinkage/PS, contact angle/CA, water sorption/WS, and water solubility/WS) were also tested. Cytotoxicity was evaluated with SRB biochemical assay. Results. No significant difference in the DTS, FS, FM, CS, CA, WS, and WS were found when 1% of ZnOn or Zn-Mt was added to the model dentin adhesive. Group Zn-Mt decreased the RM of adhesive. Groups Zn-Mt and ZnOn decreased the PS of adhesives. Group ZnOn reduced the cytotoxicity of adhesive. Group ZnOn preserved mTBS after 6 months storage without degradation areas as seen by SEM analysis. Significance. The 1 wt.% ZnOn may preserve the integrity of the hybrid layer and may reduce cytotoxicity and polymerization shrinkage of model dentin adhesive. The addition of Zn-Mt to the adhesive had no beneficial effects. (C) 2016 The Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:940 / 950
页数:11
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