Applications of Bacterial Magnetic Nanoparticles in Nanobiotechnology

被引:25
作者
Chen, Chuanfang [1 ]
Wang, Pingping [1 ]
Li, Linlin [2 ]
机构
[1] Chinese Acad Sci, Inst Elect Engn, Beijing Key Lab Bioelectromagnetism, Beijing 100190, Peoples R China
[2] Chinese Acad Sci, Tech Inst Phys & Chem, Lab Controllable Preparat & Applicat Nanomaterial, Beijing 100190, Peoples R China
基金
中国国家自然科学基金;
关键词
Bacterial Magnetic Nanoparticles; Magnetosome; Nanobitechnology; Magnetic Hyperthermia; Drug Delivery; Multimodal Imaging; Bioseparation; AMB-1 MAGNETOTACTIC BACTERIA; MAGNETOSPIRILLUM-GRYPHISWALDENSE MSR-1; FIELD CANCER-THERAPY; GENE DELIVERY-SYSTEM; SP STRAIN AMB-1; MAGNETOSOME FORMATION; ELECTRON-MICROSCOPY; DRUG-DELIVERY; CONTROLLED BIOMINERALIZATION; BIOMEDICAL APPLICATIONS;
D O I
10.1166/jnn.2016.10954
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The bacterial magnetic nanoparticle (BMP) has been well researched in nanobiotechnology as a new magnetic crystal. The BMPs are extracted from magnetotactic bacteria and under precise biological control. Compared with engineered magnetic nanoparticles synthesized by chemical approaches, BMPs have the properties of large production, monodispersity, high crystallinity, and close-to-bulk magnetization, which enable BMPs to be the highly promising magnetic nanoparticles for nanobiotechnology. In this paper, we review the biomedical applications of BMPs in magnetic hyperthermia, drug treatment with tumour and bioseparation. In addition, the biodistribution and toxicity are also reviewed.
引用
收藏
页码:2164 / 2171
页数:8
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