Protein A chromatography for antibody purification

被引：385

作者：

Hober, Sophia

Nord, Karin

Linhult, Martin

机构：

[1] Octapharma AB, S-11275 Stockholm, Sweden

[2] Affibody AB, Bromma, Sweden

[3] Royal Inst Technol, Stockholm, Sweden

来源：

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES | 2007年 / 848卷 / 01期

关键词：

affinity chromatography; cleaning-in-place (CIP); deamidation; protein A; protein engineering; stabilization;

D O I：

10.1016/j.jchromb.2006.09.030

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Staphylococcal protein A (SPA) is one of the first discovered immunoglobulin binding molecules and has been extensively studied during the past decades. Due to its affinity to immunoglobulins, SPA has found widespread use as a tool in the detection and purification of antibodies and the molecule has been further developed to one of the most employed affinity purification systems. Interestingly, a minimized SPA derivative has been constructed and a domain originating from SPA has been improved to withstand the harsh environment employed in industrial purifications. This review will focus on the development of different affinity molecules and matrices for usage in antibody purification. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：40 / 47

页数：8

共 50 条

[41] An artificial protein L for the purification of immunoglobulins and Fab fragments by affinity chromatography
Roque, ACA
Taipa, MA
Lowe, CR
JOURNAL OF CHROMATOGRAPHY A, 2005, 1064 (02) : 157 - 167
[42] Future of antibody purification
Low, Duncan
O'Leary, Rhona
Pujar, Narahari S.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2007, 848 (01): : 48 - 63
[43] Monoclonal antibody purification by affinity chromatography with ligands derived from the screening of peptide combinatory libraries
S.A. Camperi
N.B. Iannucci
G.J. Albanesi
M. Oggero Eberhardt
M. Etcheverrigaray
A. Messeguer
F. Albericio
O. Cascone
Biotechnology Letters, 2003, 25 : 1545 - 1548
[44] New tetrapeptide ligands designed for antibody purification with biomimetic chromatography: Molecular simulation and experimental validation
Wang, Rong-Zhu
Lin, Dong-Qiang
Chu, Wen-Ning
Zhang, Qi-Lei
Yao, Shan-Jing
BIOCHEMICAL ENGINEERING JOURNAL, 2016, 114 : 194 - 204
[45] Monoclonal antibody purification by affinity chromatography with ligands derived from the screening of peptide combinatory libraries
Camperi, SA
Iannucci, NB
Albanesi, GJ
Eberhardt, MO
Etcheverrigaray, M
Messeguer, A
Albericio, F
Cascone, O
BIOTECHNOLOGY LETTERS, 2003, 25 (18) : 1545 - 1548
[46] Designing new monoclonal antibody purification processes using mixed-mode chromatography sorbents
Toueille, Magali
Uzel, Audrey
Depoisier, Jean-Francois
Gantier, Rene
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2011, 879 (13-14): : 836 - 843
[47] Economic optimization of antibody capture through Protein A affinity nanofiber chromatography
Qu, Yiran
Bekard, Innocent
Hunt, Ben
Black, Jamie
Fabri, Louis
Gras, Sally L.
Kentish, Sandra. E.
BIOCHEMICAL ENGINEERING JOURNAL, 2024, 201
[48] Application of the Protein Maker as a platform purification system for therapeutic antibody research and development
Helie, Genevieve
Parat, Marie
Masse, Frederic
Gerdts, Cory J.
Loisel, Thomas P.
Matte, Allan
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2016, 14 : 238 - 244
[49] 3D-Printed microfluidic device for protein purification in batch chromatography
Habib, Taieb
Braemer, Chantal
Heuer, Christopher
Ebbecke, Jan
Beutel, Sascha
Bahnemann, Janina
LAB ON A CHIP, 2022, 22 (05) : 986 - 993
[50] Transient conformational modification of immunoglobulin G during purification by protein A affinity chromatography
Gagnon, Pete
Nian, Rui
Leong, Denise
Hoi, Aina
JOURNAL OF CHROMATOGRAPHY A, 2015, 1395 : 136 - 142

← 1 2 3 4 5 →