A versatile technique for visual enhancement of medical ultrasound images

The paper presents a versatile wavelet domain despeckling technique to visually enhance the medical ultrasound (US) images for improving the clinical diagnosis. The method uses the two-sided generalized Nakagami distribution (GND) for modeling the speckle wavelet coefficients and the signal wavelet coefficients are approximated using the generalized Gaussian distribution (GGD). Combining these statistical priors with the Bayesian maximum a posteriori (MAP) criterion, the thresholding/shrinkage estimators are derived for processing the wavelet coefficients of detail subbands. Consequently, two blind speckle suppressors named as GNDThresh and GNDShrink have been implemented and evaluated on both the artificial speckle simulated images and real US images. The experimental results demonstrate the superiority of the suggested technique both quantitatively and qualitatively as compared to other competitive schemes reported in the image denoising literature, e.g., the proposed method yields a gain of more than 0.36 dB over the best state-of-the-art despeckling method (GenLik), 0.93 dB over SRAD filter, 2.35 dB over Lee filter, and 1.34 dB over Kuan filter in terms of signal-to-noise ratio, when tested on the realistic US images. The visual comparison of despeckled US images and the higher values of quality metrics (coefficient of correlation, edge preservation index, quality index, and structural similarity index) indicate that the new method suppresses the speckle noise well while preserving the texture and organ surfaces. Further, the proposed method will be evaluated on other class of images as well as by employing multiple observer evaluation. (c) 2007 Elsevier Inc. All rights reserved.