Nanoceria exhibit redox state-dependent catalase mimetic activity

被引：921

作者：

Pirmohamed, Talib ^{[1
]}

Dowding, Janet M. ^{[1
]}

Singh, Sanjay ^{[1
]}

Wasserman, Brian ^{[1
]}

Heckert, Eric ^{[1
]}

Karakoti, Ajay S. ^{[2
,3
]}

King, Jessica E. S. ^{[2
,3
]}

Seal, Sudipta ^{[2
,3
]}

Self, William T. ^{[1
]}

机构：

[1] Burnett Sch Biomed Sci, Orlando, FL USA

[2] Univ Cent Florida, Mech Mat & Aerosp Engn Nanosci & Technol Ctr, Orlando, FL 32816 USA

[3] Univ Cent Florida, Adv Mat Proc & Anal Ctr, Orlando, FL 32816 USA

来源：

CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 16期

关键词：

SUPEROXIDE-DISMUTASE; OXIDE NANOPARTICLES; OXIDATIVE STRESS; CERIUM; NANOSTRUCTURES;

D O I：

10.1039/b922024k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this study we have found that cerium oxide nanoparticles exhibit catalase mimetic activity. Surprisingly, the catalase mimetic activity correlates with a reduced level of cerium in the +3 state, in contrast to the relationship between surface charge and superoxide scavenging properties.

引用

页码：2736 / 2738

页数：3

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