Heterogeneous Suzuki and copper-free Sonogashira cross-coupling reactions catalyzed by a reusable palladium(II) complex in water medium

被引：114

作者：

Islam, S. M. ^{[1
]}

Mondal, Paramita ^{[1
]}

Roy, Anupam Singha ^{[1
]}

Mondal, Sanchita ^{[1
]}

Hossain, Dilder ^{[1
]}

机构：

[1] Kalyani Univ, Dept Chem, Nadia 741235, W Bengal, India

来源：

TETRAHEDRON LETTERS | 2010年 / 51卷 / 15期

关键词：

Suzuki reaction; Sonogashira reaction; Water medium; Polystyrene anchored Pd(II) azo complex; PCP-PINCER COMPLEXES; SUPPORTED PALLADIUM(0); PALLADACYCLE CATALYST; AEROBIC CONDITIONS; TRANSITION-METALS; AQUEOUS-MEDIA; HECK; SILICA; CARBON; DERIVATIVES;

D O I：

10.1016/j.tetlet.2010.02.079

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new polystyrene anchored Pd(II) azo complex has been synthesized and characterized. The present Pd(II) azo complex behaves as a very efficient heterogeneous catalyst in the Suzuki coupling and Sonogashira coupling reaction in water medium. Aryl halides, coupled with phenylboronic acids (Suzuki-Miyaura reaction) or terminal alkyne (Sonogashira reaction), smoothly afford the corresponding cross-coupling products in excellent yields (83-100% yield for Suzuki reaction and 68-96% yield for Sonogashira reaction of aryl halides) under phosphine-free reaction conditions in the presence of polystyrene anchored Pd(II) azo complex catalyst in water medium. Furthermore, the catalyst has shown good thermal stability and recyclability. This polymer-supported Pd(II) catalyst could be easily recovered by simple filtration of the reaction mixture and reused for more than six consecutive trials without a significant loss of its catalytic activity. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：2067 / 2070

页数：4

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