Thyroid Abnormalities in Heart Failure

被引:13
作者
Danzi, Sara [1 ]
Klein, Irwin [2 ]
机构
[1] CUNY, Queensborough Community Coll, Dept Biol Sci & Geol, 222-05 56th Ave, Bayside, NY 11364 USA
[2] NYU, Sch Med, 555 Broadhollow Rd,Suite 229, Melville, NY 11747 USA
关键词
Triiodothyronine; T-3; Nonthyroidal illness; Cardiac; Thyroid hormone; Low T-3 syndrome; Cardiovascular; HORMONE METABOLISM; NATRIURETIC PEPTIDE; LOW-T-3; SYNDROME; TRIIODOTHYRONINE; DISEASE; REPLACEMENT; ILLNESS; DEATH; HYPOTHYROIDISM; ASSOCIATION;
D O I
10.1016/j.hfc.2019.08.002
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The effects of hyperthyroidism and hypothyroidism on the heart and cardiovascular system are well documented. It has also been shown that various forms of heart disease including but not limited to congenital, hypertensive, ischemic, cardiac surgery, and heart transplantation cause an alteration in thyroid function tests including a decrease in serum liothyronine (T-3). This article discusses the basic science and clinical data that support the hypothesis that these changes pose pathophysiologic and potential novel therapeutic challenges.
引用
收藏
页码:1 / +
页数:10
相关论文
共 41 条
  • [1] Thyroid hormone metabolism in patients with congestive heart failure: The low triiodothyronine state
    Ascheim, DD
    Hryniewicz, K
    [J]. THYROID, 2002, 12 (06) : 511 - 515
  • [2] Induced illness in interleukin-6 (IL-6) knock-out mice: A causal role of IL-6 in the development of the low 3,5,3'-triiodothyronine syndrome
    Boelen, A
    Maas, MAW
    Lowik, CWGM
    Platvoet, MC
    Wiersinga, WM
    [J]. ENDOCRINOLOGY, 1996, 137 (12) : 5250 - 5254
  • [3] Hypothyroidism and atherosclerosis
    Cappola, AR
    Ladenson, PW
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2003, 88 (06) : 2438 - 2444
  • [4] The Low Triiodothyronine Syndrome: A Strong Predictor of Low Cardiac Output and Death in Patients Undergoing Coronary Artery Bypass Grafting
    Cerillo, Alfredo Giuseppe
    Storti, Simona
    Kallushi, Enkel
    Haxhiademi, Dorela
    Miceli, Antonio
    Murzi, Michele
    Berti, Sergio
    Glauber, Mattia
    Clerico, Aldo
    Iervasi, Giorgio
    [J]. ANNALS OF THORACIC SURGERY, 2014, 97 (06) : 2089 - 2096
  • [5] Impact of Triiodothyronine and N-Terminal Pro-B-Type Natriuretic Peptide on the Long-Term Survival of Critically Ill Patients With Acute Heart Failure
    Chuang, Chun-Pin
    Jong, Yuh-Shiun
    Wu, Chang-Yu
    Lo, Huey-Ming
    [J]. AMERICAN JOURNAL OF CARDIOLOGY, 2014, 113 (05) : 845 - 850
  • [6] Triiodothyronine-mediated myosin heavy chain gene transcription in the heart
    Danzi, S
    Ojamaa, K
    Klein, I
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2003, 284 (06): : H2255 - H2262
  • [7] Thyroid Disease and the Cardiovascular System
    Danzi, Sara
    Klein, Irwin
    [J]. ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA, 2014, 43 (02) : 517 - +
  • [8] Thyroid Hormone and the Cardiovascular System
    Danzi, Sara
    Klein, Irwin
    [J]. MEDICAL CLINICS OF NORTH AMERICA, 2012, 96 (02) : 257 - +
  • [9] Danzi S, 2009, THYROID AND HEART FAILURE: FROM PATHOPHYSIOLOGY TO CLINICS, P97, DOI 10.1007/978-88-470-1143-4_10
  • [10] Nongenomic actions of thyroid hormone on the heart
    Davis, PJ
    Davis, FB
    [J]. THYROID, 2002, 12 (06) : 459 - 466