Vascular pathologic changes in the flexor tenosynovium (subsynovial connective tissue) in idiopathic carpal tunnel syndrome

被引:58
作者
Jinrok, O
Zhao, CF
Amadio, PC
An, KN
Zobitz, ME
Wold, LE
机构
[1] Mayo Clin & Mayo Fdn, Orthopaed Biomech Lab, Rochester, MN 55905 USA
[2] Mayo Clin & Mayo Fdn, Dept Pathol, Rochester, MN 55905 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1016/j.orthres.2004.03.005
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
We used the Verhoeff-van Gieson stain method to identify histopathology and to localize elastin in the subsynovial connective tissue of the tendon sheath (SSCT) of the middle finger flexor digitorum superficialis (FDS) within the carpal tunnel in 10 carpal tunnel syndrome (CTS) patients and 10 control cadaver specimens. Normal SSCT stained for elastin abundantly around blood vessels and within vessel walls. The typical pathologic findings of CTS patients SSCT included vascular proliferation, vascular hypertrophy, and vascular obstruction with wall thickening. There was a decreased amount of elastin in the blood vessel walls and around the vessels in the CTS patients as well. The changes in the carpal tunnel patients were particularly remarkable in that the patients were younger than the controls, yet showed findings more characteristic of chronic degeneration. (C) 2004 Orthopaedic Research Society. Published by Elsevier Ltd. All rights reserved.
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页码:1310 / 1315
页数:6
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