Metabolic and Molecular Imaging of Atherosclerosis and Venous Thromboembolism

被引：29
作者：
Osborn, Eric A. [1 ,2 ]
Kessinger, Chase W. [1 ]
Tawakol, Ahmed [1 ]
Jaffer, Farouc A. [1 ]
机构：
[1] Harvard Med Sch, Massachusetts Gen Hosp, Cardiol Div, Cardiovasc Res Ctr, Boston, MA USA
[2] Harvard Med Sch, Beth Israel Deaconess Med Ctr, Cardiol Div, Boston, MA USA
来源：
JOURNAL OF NUCLEAR MEDICINE | 2017年 / 58卷 / 06期
关键词：
molecular imaging; atherosclerosis; near infrared; fluorescence; PET; venous thromboembolism; FDG PET/CT; ARTERIAL INFLAMMATION; PLAQUE INFLAMMATION; F-18-FDG UPTAKE; CAROTID-ARTERY; RISK; THROMBOSIS; PREDICTION; INHIBITOR; EFFICACY;
D O I：
10.2967/jnumed.116.182873
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Metabolic and molecular imaging continues to advance our understanding of vascular disease pathophysiology. At present, F-18-FDG PET imaging is the most widely used clinical tool for metabolic and molecular imaging of atherosclerosis. However, novel nuclear tracers and intravascular optical near-infrared fluorescence imaging catheters are emerging to assess new biologic targets in vivo and in coronary arteries. This review highlights current metabolic and molecular imaging clinical and near-clinical applications within atherosclerosis and venous thromboembolism, and explores the potential for metabolic and molecular imaging to affect patient-level risk prediction and disease treatment.
引用
收藏
页码：871 / 877
页数：7
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