Generation of CsI Cluster Ions for Mass Calibration in Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry

被引：43
|
作者：
Lou, Xianwen [1 ]
van Dongen, Joost L. J. [1 ]
Meijer, E. W. [1 ]
机构：
[1] Eindhoven Univ Technol, Lab Macromol & Organ Chem, NL-5600 MB Eindhoven, Netherlands
来源：
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY | 2010年 / 21卷 / 07期
关键词：
TIME-OF-FLIGHT; DESORPTION IONIZATION; ACCURATE MASS; DELAYED EXTRACTION; HIGH-RESOLUTION; ELECTROSPRAY-IONIZATION; MALDI; SPECTRA; PROTEINS; VELOCITY;
D O I：
10.1016/j.jasms.2010.02.029
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
A simple method was developed for the generation of cesium iodide (CsI) cluster ions up to m/z over 20,000 in matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS). Calibration ions in both positive and negative ion modes can readily be generated from a single MALDI spot of CsI(3) with 2-[(2E)-3-(4-tert-butylphenyl)-2-methylprop-2-enylidene] malononitrile (DCTB) matrix. The major cluster ion series observed in the positive ion mode is [(CsI)(n)Cs](+), and in the negative ion mode is [(CsI)(n)I](-). In both cluster series, ions spread evenly every 259.81 units. The easy method described here for the production of CsI cluster ions should be useful for MALDI MS calibrations. (J Am Soc Mass Spectrom 2010, 21, 1223-1226) (C) 2010 American Society for Mass Spectrometry
引用
收藏
页码：1223 / 1226
页数：4
相关论文
共 50 条
  • [31] Interfacing matrix-assisted laser desorption/ionization mass spectrometry with column and planar separations
    A. I. Gusev
    Fresenius' Journal of Analytical Chemistry, 2000, 366 : 691 - 700
  • [32] FRAGMENTATION ANALYSIS OF OLIGONUCLEOTIDES BY MATRIX-ASSISTED LASER DESORPTION/IONIZATION (MALDI) MASS SPECTROMETRY
    Y. C. Leo Li
    T. W. Dominic Chan (Department of Chemistry
    Chinese University of Hong Kong Shatin
    New Territories
    The Chinese University of Hong Kong
    Shatin
    New Territories
    Hong Kong)
    质谱学报, 1999, (Z1) : 77 - 78
  • [33] Perspectives in the glycosciences – matrix-assisted laser desorption/ionization (MALDI) mass spectrometry of carbohydrates
    David J Harvey
    Bernhard Kuster
    Thomas J.P Naven
    Glycoconjugate Journal, 1998, 15 : 333 - 338
  • [34] Systematic assessment of surfactants for matrix-assisted laser desorption/ionization mass spectrometry imaging
    Banstola, Bijay
    Grodner, Eulalie T.
    Cao, Fan
    Donnarumma, Fabrizio
    Murray, Kermit K.
    ANALYTICA CHIMICA ACTA, 2017, 963 : 76 - 82
  • [35] The influence of laser fluence on ion yield in matrix-assisted laser desorption ionization mass spectrometry
    Westmacott, G
    Ens, W
    Hillenkamp, F
    Dreisewerd, K
    Schürenberg, M
    INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2002, 221 (01) : 67 - 81
  • [36] Matrix-assisted laser desorption/ionization imaging mass spectrometry of pollen grains and their mixtures
    Weidner, Steffen
    Schultze, Rolf-Dieter
    Enthaler, Bernd
    RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2013, 27 (08) : 896 - 903
  • [37] Matrix-Assisted Laser Desorption Ionization Imaging Mass Spectrometry: In Situ Molecular Mapping
    Angel, Peggi M.
    Caprioli, Richard M.
    BIOCHEMISTRY, 2013, 52 (22) : 3818 - 3828
  • [38] Reactive Matrices for Analytical Matrix-Assisted Laser Desorption/Ionization (MALDI) Mass Spectrometry
    Borisov, Roman S.
    Matveeva, Mariya D.
    Zaikin, Vladimir G.
    CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY, 2021, 53 (05) : 1027 - 1043
  • [39] Basic poly(propylene glycols) as reference compounds for internal mass calibration in positive-ion matrix-assisted laser desorption/ionization mass spectrometry
    Gross, Juergen H.
    EUROPEAN JOURNAL OF MASS SPECTROMETRY, 2017, 23 (06) : 411 - 416
  • [40] Online Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry with In situ Mixing
    Liang, Miao
    Shu, Jinian
    Zhang, Peng
    Li, Yueyan
    Sun, Wanqi
    ANALYTICAL LETTERS, 2015, 48 (16) : 2553 - 2565
12345