Generation of CsI Cluster Ions for Mass Calibration in Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry

被引：43
|
作者：
Lou, Xianwen [1 ]
van Dongen, Joost L. J. [1 ]
Meijer, E. W. [1 ]
机构：
[1] Eindhoven Univ Technol, Lab Macromol & Organ Chem, NL-5600 MB Eindhoven, Netherlands
来源：
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY | 2010年 / 21卷 / 07期
关键词：
TIME-OF-FLIGHT; DESORPTION IONIZATION; ACCURATE MASS; DELAYED EXTRACTION; HIGH-RESOLUTION; ELECTROSPRAY-IONIZATION; MALDI; SPECTRA; PROTEINS; VELOCITY;
D O I：
10.1016/j.jasms.2010.02.029
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
A simple method was developed for the generation of cesium iodide (CsI) cluster ions up to m/z over 20,000 in matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS). Calibration ions in both positive and negative ion modes can readily be generated from a single MALDI spot of CsI(3) with 2-[(2E)-3-(4-tert-butylphenyl)-2-methylprop-2-enylidene] malononitrile (DCTB) matrix. The major cluster ion series observed in the positive ion mode is [(CsI)(n)Cs](+), and in the negative ion mode is [(CsI)(n)I](-). In both cluster series, ions spread evenly every 259.81 units. The easy method described here for the production of CsI cluster ions should be useful for MALDI MS calibrations. (J Am Soc Mass Spectrom 2010, 21, 1223-1226) (C) 2010 American Society for Mass Spectrometry
引用
收藏
页码：1223 / 1226
页数：4
相关论文
共 50 条
  • [1] Matrix-Assisted Laser Desorption/Ionization Imaging Mass Spectrometry
    Zaima, Nobuhiro
    Hayasaka, Takahiro
    Goto-Inoue, Naoko
    Setou, Mitsutoshi
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2010, 11 (12) : 5041 - 5056
  • [2] Matrix ions as internal standard for high mass accuracy matrix-assisted laser desorption/ionization mass spectrometry imaging
    Treu, Axel
    Roempp, Andreas
    RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2021, 35 (16)
  • [3] Effects of substrate surfaces in matrix-assisted laser desorption/ionization mass spectrometry
    Togashi, Hisashi
    Kobayashi, Yoshinori
    RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2009, 23 (18) : 2952 - 2958
  • [4] Focused Electrospray Deposition for Matrix-assisted Laser Desorption/Ionization Mass Spectrometry
    Jeong, Kyung Hwan
    Seo, Jongcheol
    Yoon, Hye-Joo
    Shin, Seung Koo
    BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2010, 31 (08): : 2293 - 2298
  • [5] Recent advancements in matrix-assisted laser desorption/ionization mass spectrometry imaging
    Baker, Teesha C.
    Han, Jun
    Borchers, Christoph H.
    CURRENT OPINION IN BIOTECHNOLOGY, 2017, 43 : 62 - 69
  • [6] Matrix-assisted laser desorption ionization imaging mass spectrometry in lipidomics
    Fernandez, J. A.
    Ochoa, B.
    Fresnedo, O.
    Giralt, M. T.
    Rodriguez-Puertas, R.
    ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2011, 401 (01) : 29 - 51
  • [7] Matrix-assisted laser desorption ionization imaging mass spectrometry in lipidomics
    J. A. Fernández
    B. Ochoa
    O. Fresnedo
    M. T. Giralt
    R. Rodríguez-Puertas
    Analytical and Bioanalytical Chemistry, 2011, 401 : 29 - 51
  • [8] Dual polarity accurate mass calibration for electrospray ionization and matrix-assisted laser desorption/ionization mass spectrometry using maltooligosaccharides
    Clowers, Brian H.
    Dodds, Eric D.
    Seipert, Richard R.
    Lebrilla, Carlito B.
    ANALYTICAL BIOCHEMISTRY, 2008, 381 (02) : 205 - 213
  • [9] A thiophene-containing compound as a matrix for matrix-assisted laser desorption/ionization mass spectrometry and the electrical conductivity of matrix crystals
    Yasuda, Akikazu
    Ishimaru, Takayuki
    Nishihara, Shogo
    Sakai, Masamichi
    Kawasaki, Hideya
    Arakawa, Ryuichi
    Shigeri, Yasushi
    EUROPEAN JOURNAL OF MASS SPECTROMETRY, 2013, 19 (01) : 29 - 37
  • [10] A binary matrix for improved detection of phosphopeptides in matrix-assisted laser desorption/ionization mass spectrometry
    Zhou, Li-Hua
    Kang, Gum-Yong
    Kim, Kwang Pyo
    RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2009, 23 (15) : 2264 - 2272
12345