Palliative care in metastatic head and neck cancer

被引：13

作者：

Civantos, Alyssa M. ^{[1
]}

Prasad, Aman ^{[1
]}

Carey, Ryan M. ^{[2
]}

Bur, Andres M. ^{[3
]}

Mady, Leila J. ^{[2
,4
]}

Brody, Robert M. ^{[2
]}

Rajasekaran, Karthik ^{[2
]}

Cannady, Steven B. ^{[2
]}

Hartner, Lee ^{[5
]}

Ibrahim, Said A. ^{[6
]}

Newman, Jason G. ^{[2
]}

Brant, Jason A. ^{[2
]}

机构：

[1] Univ Penn, Perelman Sch Med, Philadelphia, PA 19104 USA

[2] Univ Penn, Perelman Sch Med, Dept Otorhinolaryngol Head & Neck Surg, Philadelphia, PA 19104 USA

[3] Univ Kansas, Dept Otolaryngol Head & Neck Surg, Kansas City, KS USA

[4] Univ Penn, Leonard Davis Inst Hlth Econ, Philadelphia, PA 19104 USA

[5] Univ Penn, Dept Hematol, Med Oncol, Philadelphia, PA 19104 USA

[6] Weill Cornell Med, Dept Healthcare Policy & Res, New York, NY USA

来源：

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2021年 / 43卷 / 09期

关键词：

end of life care; head and neck cancer; metastatic cancer; palliative care; socioeconomic factors; END-OF-LIFE; PATTERNS; SURVIVAL;

D O I：

10.1002/hed.26761

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

Background Due to inherent impact on quality of life, metastatic head and neck cancer patients are well-suited to benefit from palliative care (PC). Our objective was to examine factors that shape PC utilization and implications for overall survival in stage IVc head and neck cancer patients. Methods A retrospective study of patients with stage IVc head and neck cancer in the National Cancer Database from 2004 and 2015 was conducted. Results 7794 cases met inclusion criteria, of which 19.3% received PC. PC use was associated with more recent years of diagnosis, Northeast facility geography, and non-private insurances (p < 0.05). Compared to no PC, "interventional" PC, defined as palliative surgery, radiation, and/or chemotherapy, and "pain management only" PC were associated with lower overall survival (p < 0.05). Conclusions PC use increased over time and was associated with demographic and clinical factors. There remains opportunity for improvement in optimal implementation of palliative care.

引用

页码：2764 / 2777

页数：14

共 50 条

[31] The role of palliative care in relapsed and metastatic head and neck cancer patients in a single ESMO integrated oncology and palliative care centre (July, 10.1007/s00405-022-07535-z, 2022) [J].

Espeli, Vittoria Guro ;

Fusi-Schmidhauser, Tanja ;

Mangan, Dylan ;

Gamondi, Claudia .

EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, 2022, 279 (12) :5903-5903

[32] The Utilization of Specialist Palliative Care and Other Health Care Services at the End of Life Among Patients with Head and Neck Cancer: A Nationwide Cohort Study [J].

Merikari, Martti ;

Akren, Outi ;

Nuutinen, Mikko ;

Makitie, Antti ;

Saarto, Tiina ;

Carpen, Timo .

ONCOLOGY AND THERAPY, 2025, 13 (02) :397-408

[33] Navigating the impact of COVID-19 on palliative care for head and neck cancer [J].

Singh, Arjun Gurmeet ;

Deodhar, Jayita ;

Chaturvedi, Pankaj .

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2020, 42 (06) :1144-1146

[34] Palliative care interventions for patients with head and neck cancer: protocol for a scoping review [J].

Ratnasekera, Nadisha ;

Fazelzad, Rouhi ;

Bagnarol, Rebecca ;

Cunha, Vanessa ;

Zimmermann, Camilla ;

Lau, Jenny .

BMJ OPEN, 2023, 13 (11)

[35] Integration of Palliative Care as a Part of the Multidisciplinary Management of Patients with Head and Neck Cancer [J].

Makitie, Antti ;

Saarto, Tiina .

ONCOLOGY AND THERAPY, 2025,

[36] Gefitinib (ZD1839, Iressa™) as palliative treatment in recurrent or metastatic head and neck cancer [J].

A M Kirby ;

R P A'Hern ;

C D'Ambrosio ;

M Tanay ;

K N Syrigos ;

S J Rogers ;

C Box ;

S A Eccles ;

C M Nutting ;

K J Harrington .

British Journal of Cancer, 2006, 94 :631-636

[37] Gefitinib (ZD1839, IressaTM) as palliative treatment in recurrent or metastatic head and neck cancer [J].

Kirby, AM ;

A'Hern, RP ;

D'Ambrosio, C ;

Tanay, M ;

Syrigos, KN ;

Rogers, SJ ;

Box, C ;

Eccles, SA ;

Nutting, CM ;

Harrington, KJ .

BRITISH JOURNAL OF CANCER, 2006, 94 (05) :631-636

[38] Palliative radiotherapy for locally advanced non-metastatic head and neck cancer: A systematic review [J].

Iqbal, Muhammad Shahid ;

Kelly, Charles ;

Kovarik, Josef ;

Goranov, Bojidar ;

Shaikh, Ghazia ;

Morgan, David ;

Dobrowsky, Werner ;

Paleri, Vinidh .

RADIOTHERAPY AND ONCOLOGY, 2018, 126 (03) :558-567

[39] Do palliative embolization in unresectable, unsalvageable recurrent and metastatic head and neck cancer patients help? [J].

Nitin Shetty ;

Nandini Menon ;

Shivakumar Thiagarajan ;

Shikar Sawhney ;

Suyash Kulkarni ;

Devendra Chaukar .

European Archives of Oto-Rhino-Laryngology, 2021, 278 :3401-3407

[40] Do palliative embolization in unresectable, unsalvageable recurrent and metastatic head and neck cancer patients help? [J].

Shetty, Nitin ;

Menon, Nandini ;

Thiagarajan, Shivakumar ;

Sawhney, Shikar ;

Kulkarni, Suyash ;

Chaukar, Devendra .

EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, 2021, 278 (09) :3401-3407

← 1 2 3 4 5 →