Chemical composition, evaluation of antibacterial activity and toxicity of the essential oils from Lantana camara L. and Lantana sp.

被引:23
|
作者
da Costa, Jose G. M. [1 ]
de Sousa, Erlanio O. [1 ]
Rodrigues, Fabiola F. G. [1 ]
de Lima, Sidney G. [2 ]
Braz Filho, Raimundo [3 ]
机构
[1] Univ Reg Cariri, Programa Posgrad Bioprospeccao Mol, Lab Pesquisas Prod Nat, BR-63105000 Crato, CE, Brazil
[2] Univ Fed Piaui, Dept Quim, BR-64049550 Teresina, PI, Brazil
[3] Univ Estadual Norte Fluminense, Programa Posgrad Ciencias Nat, BR-28013602 Rio De Janeiro, Brazil
关键词
Lantana; Verbenaceae; essential oils; terpernoids; biological activities; PLANTS; NORTHEAST;
D O I
10.1590/S0102-695X2009000500010
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
"Chemical composition, evaluation of antibacterial activity and toxicity of the essential oils from Lantana camara L. and Lantana sp.". The essential oils from Lantana camara L. and Lantana sp. Verbenaceae, were obtained by hydrodistillation and analyzed by GUMS. This GUMS analysis revealed the sesquiterpenoids,bicyclogermacrene (19.42%), isocaryophyllene (16.70%), valencene (12.94%) an and germacrene D (12.34%) as majoritaries in the essential oil of L Camara, and bicyclogermacrene (13.93%), germacrene D (27.54 and beta-caryophyllene (31,50%) in the essential oil from Lantana sp. The two essential oils were evaluated to antibacterial activity and toxicity using Artemia salina. The results revealed considerable antibacterial activity for essential, oil' from L. Camara, meanly for Proteus vulgaris (ATCC 13315) and e-Escherichia coli (ATCC 25922). The essential oil of Lantana sp. showed major activity or Sthaphylococcus aureus (ATCC I 10390). The evaluation of toxicity CL50 revealed results with minor values to limit pattern of 1000 mu g/mL..
引用
收藏
页码:710 / 714
页数:5
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