Genome sequence of a multidrug-resistant Corynebacterium striatum isolated from bloodstream infection from a nosocomial outbreak in Rio de Janeiro, Brazil

被引：15
作者：
Ramos, Juliana Nunes [1 ,2 ]
Rodrigues, Izabel dos Santos [1 ,3 ]
Pereira Baio, Paulo Victor [2 ]
Carneiro Veras, Joao Flavio [1 ]
Juca Ramos, Rommel Thiago [4 ]
Pacheco, Luis G. C. [5 ]
Azevedo, Vasco Ariston [6 ]
Hirata Junior, Raphael [2 ]
Marin, Michel Abanto [7 ]
de Mattos-Guaraldi, Ana Luiza [2 ]
Vieira, Veronica Viana [3 ]
机构：
[1] Fundacao Oswaldo Cruz, Fiocruz, Inst Nacl Controle Qualidade Saude, Rio De Janeiro, RJ, Brazil
[2] Univ Estado Rio de Janeiro, Fac Ciencias Med, Lab Difteria & Corinebacterias Importancia Clin, Rio De Janeiro, RJ, Brazil
[3] Fundacao Oswaldo Cruz, Fiocruz, Inst Oswaldo Cruz, Lab Interdisciplinar Pesquisas Med, Rio De Janeiro, RJ, Brazil
[4] Univ Fed Para, Ctr Genom & Biol Sistemas, Belem, Para, Brazil
[5] Univ Fed Bahia, Inst Ciencias Saude, Salvador, BA, Brazil
[6] Univ Fed Minas Gerais, Inst Ciencias Biol, Belo Horizonte, MG, Brazil
[7] Univ La Frontera, Sci & Technol Bioresource Nucleus, Temuco, Chile
来源：
MEMORIAS DO INSTITUTO OSWALDO CRUZ | 2018年 / 113卷 / 09期
关键词：
multidrug-resistant; Corynebacterium striatum; bloodstream infection; CRISPR-Cas; spaDEF cluster; ENDOCARDITIS;
D O I：
10.1590/0074-02760180051
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
Multidrug-resistant (MDR) Corynebacterium striatum has been cited with increased frequency as pathogen of nosocomial infections. In this study, we report the draft genome of a C. striatum isolated from a patient with blood-stream infection in a hospital of Rio de Janeiro, Brazil. The isolate presented susceptibility only to tetracycline, vancomycin and linezolid. The detection of various antibiotic resistance genes is fully consistent with previously observed multidrug-resistant pattern in Corynebacterium spp. A large part of the pTP10 plasmid of MDR C. striatum M82B is present in the genome of our isolate. A SpaDEF cluster and seven arrays of CRISPR-Cas were found.
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页数：5
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