A novel coumarin-based water-soluble fluorescent probe for endogenously generated SO2 in living cells

被引：37

作者：

Yang, Jin ^{[1
]}

Li, Kun ^{[1
]}

Hou, Ji-Ting ^{[1
]}

Lu, Chun-Yan ^{[2
]}

Li, Ling-Ling ^{[1
]}

Yu, Kang-Kang ^{[1
]}

Yu, Xiao-Qi ^{[1
]}

机构：

[1] Sichuan Univ, Coll Chem, Minist Educ, Key Lab Green Chem & Technol, Chengdu 610064, Peoples R China

[2] Sichuan Univ, West China Hosp, Dept Radiol, Chengdu 610064, Peoples R China

来源：

SCIENCE CHINA-CHEMISTRY | 2017年 / 60卷 / 06期

基金：

中国国家自然科学基金;

关键词：

endogenously generated SO2; fluorescent probe; bioimaging; SULFUR-DIOXIDE DERIVATIVES; CAPILLARY ELECTROPHORETIC DETERMINATION; THEORETICAL CALCULATIONS; AIR-POLLUTION; SULFITE; MITOCHONDRIA; BISULFITE; DESIGN; INJURY; DYES;

D O I：

10.1007/s11426-016-0411-7

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel coumarin-based "turn-on" fluorescent probe SS-1 was developed for selective detection of SO2 derivatives in 100% water solution among reactive sulfur species (RSS). The detection limit of the method was 91.7 nM. Moreover, the probe exhibited low cytotoxicity and was successfully applied in the imaging of endogenously generated SO2 in HeLa cells.

引用

页码：793 / 798

页数：6

共 45 条

[21] A mitochondria-targeted fluorescent probe for ratiometric detection of endogenous sulfur dioxide derivatives in cancer cells [J].

Li, Dong-Peng ;

Wang, Zhao-Yang ;

Cao, Xiang-Jian ;

Cui, Jie ;

Wang, Xin ;

Cui, Hao-Zhong ;

Miao, Jun-Ying ;

Zhao, Bao-Xiang .

CHEMICAL COMMUNICATIONS, 2016, 52 (13) :2760-2763

[22] Delayed rectifier potassium channels are involved in SO2 derivative-induced hippocampal neuronal injury [J].

Li, Guangke ;

Sang, Nan .

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2009, 72 (01) :236-241

[23] A dinuclear iridium(III) complex as a visual specific phosphorescent probe for endogenous sulphite and bisulphite in living cells [J].

Li, Guanying ;

Chen, Yu ;

Wang, Jinquan ;

Lin, Qian ;

Zhao, Jing ;

Ji, Liangnian ;

Chao, Hui .

CHEMICAL SCIENCE, 2013, 4 (12) :4426-4433

[24] Regulatory effects of sulfur dioxide on the development of atherosclerotic lesions and vascular hydrogen sulfide in atherosclerotic rats [J].

Li, Wei ;

Tang, Chaoshu ;

Jin, Hongfang ;

Du, Junbao .

ATHEROSCLEROSIS, 2011, 215 (02) :323-330

[25] Endogenous sulfur dioxide protects against isoproterenol-induced myocardial injury and increases myocardial antioxidant capacity in rats [J].

Liang, Yinfang ;

Liu, Die ;

Ochs, Todd ;

Tang, Chaoshu ;

Chen, Stella ;

Zhang, Suqing ;

Geng, Bin ;

Jin, Hongfang ;

Du, Junbao .

LABORATORY INVESTIGATION, 2011, 91 (01) :12-23

[26] Chemical probes for molecular imaging and detection of hydrogen sulfide and reactive sulfur species in biological systems [J].

Lin, Vivian S. ;

Chen, Wei ;

Xian, Ming ;

Chang, Christopher J. .

CHEMICAL SOCIETY REVIEWS, 2015, 44 (14) :4596-4618

[27]

Liu Y, 2015, CHEM COMMUN, V51, P10236, DOI [10.3778/j.issn.1002-8331.1405-0213, 10.1039/c5cc03055b]

[28] Design, Synthesis, and Evaluation of Thiol-Activated Sources of Sulfur Dioxide (SO2) as Antimycobacterial Agents [J].

Malwal, Satish R. ;

Sriram, Dharmarajan ;

Yogeeswari, Perumal ;

Konkimalla, V. Badireenath ;

Chakrapani, Harinath .

JOURNAL OF MEDICINAL CHEMISTRY, 2012, 55 (01) :553-557

[29] DNA damaging effects of sulfur dioxide derivatives in cells from various organs of mice [J].

Meng, ZQ ;

Qin, GH ;

Zhang, B ;

Bai, JL .

MUTAGENESIS, 2004, 19 (06) :465-468

[30] Environmental-induced oxidative stress in neurodegenerative disorders and aging [J].

Migliore, Lucia ;

Coppede, Fabio .

MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, 2009, 674 (1-2) :73-84

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