Catalase activity in human erythrocytes: Effect of phenoxyherbicides and their metabolites

被引:46
|
作者
Bukowska, B [1 ]
Chajdys, A [1 ]
Duda, W [1 ]
Duchnowiz, P [1 ]
机构
[1] Univ Lodz, Dept Biophys & Environm Pollut, PL-90237 Lodz, Poland
关键词
catalase; 2,4-dichlorophenoxyacetic acid (2,4-D); 4-chloro-2-methylphenoxyacetic acid (MCPA); 2,4-dichlorophenol (2,4-DCP); 2,4,5-trichlorophenol (2,4,5-TCP); 2,4-dimethylphenol (2,4-DMP);
D O I
10.1006/cbir.2000.0553
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The effects of exposure to different concentrations of phenoxyherbicides and their metabolites were studied in human erythrocytes, with particular attention to catalase (CAT-EC. 1.11.1.6-hydrogen peroxide: hydro gen peroxide oxidoreductase). 4-chloro-2-methylphenoxyacetic acid (MCPA), 2,4-dimethylphenol (2,4-DMP) and 2,4-dichlorophenoxyacetic acid (2,4-D) did not affect CAT activity, but 2,4-dichlorophenol (2,4-DCP) and 2,4,5-trichlorophenol (2,4,5-TCP) decrease its activity, the latter being the more inhibitory. (C) 2000 Academic Press.
引用
收藏
页码:705 / 711
页数:7
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