Renal Cell Carcinoma Associated With Xp11.2 Translocations, Report of a Case

被引：5

作者：

Jing, HongBiao ^{[1
]}

Tai, Yanhong

Xu, Dazhou

Yang, Fan

Geng, Ming

机构：

[1] Jinan Gen Hosp, Dept Pathol, Jinan 250031, Peoples R China

来源：

UROLOGY | 2010年 / 76卷 / 01期

关键词：

GENE FUSION; TFE3; GENE; KIDNEY; NEOPLASMS;

D O I：

10.1016/j.urology.2009.07.1276

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Renal cell carcinomas (RCCs) associated with Xp11.2 translocations (Xp11.2 translocation RCCs) are rare and occur predominantly in children and adolescents. A case of such tumor in a 12-year boy is reported. Grossly the cut surface of the ill-defined mass was polychromatic, containing areas of hemorrhage and necrosis. Microscopically, the tumor was composed of epithelioid cells with clear to weakly eosinophilic cytoplasm arranged in nested, alveolar, and pseudopapillary formations. Immunohistochemically, the neoplastic cells were positive for transcription factor E3 and CD10. We concluded that this case was an Xp11.2 translocation RCC. UROLOGY 76: 156-158, 2010. (C) 2010 Elsevier Inc.

引用

页码：156 / 158

页数：3

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