Immunotherapy of Rheumatoid Arthritis Targeting Inflammatory Cytokines and Autoreactive T Cells

被引：22
|
作者：
Chen, Guangjie [1 ]
机构：
[1] Shanghai Jiao Tong Univ, Sch Med, Inst Med Sci, Dept Immunol, Shanghai 200025, Peoples R China
来源：
ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS | 2010年 / 58卷 / 01期
关键词：
Rheumatoid arthritis; Immunotherapy; Inflammatory cytokines; Autoreactive T cells; Regulatory T cells; Th17; cells; PLACEBO-CONTROLLED TRIAL; NECROSIS-FACTOR-ALPHA; COLLAGEN-INDUCED ARTHRITIS; ANTI-INTERLEUKIN-6 RECEPTOR ANTIBODY; CONTROLLED CLINICAL-TRIAL; LONG-TERM SAFETY; PHASE-III TRIAL; DOUBLE-BLIND; TNF-ALPHA; RANDOMIZED-TRIAL;
D O I：
10.1007/s00005-009-0058-1
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Rheumatoid arthritis is a chronic disorder for which there is no known cure. Concentrating on specific elements of the abnormal immune response that characterizes the disease, scientists are reaching into biotechnology's bag of tricks to develop immunotherapeutic techniques. This paper will present some advances in the immunotherapy of rheumatoid arthritis targeting inflammatory cytokines and autoreactive T cells.
引用
收藏
页码：27 / 36
页数：10
相关论文
共 50 条
  • [41] Inflammatory cytokines of rheumatoid arthritis (RA) and gastrointestinal cancer (GIC)
    Davidhi, G.
    Kullolli, S.
    Spahiu, O.
    Sallaku, A.
    Harizi, I.
    Cota, J.
    Hoxha, F.
    ANNALS OF ONCOLOGY, 2016, 27 : 56 - 57
  • [42] Involvement of the Circadian Rhythm and Inflammatory Cytokines in the Pathogenesis of Rheumatoid Arthritis
    Yoshida, Kohsuke
    Hashimoto, Teppei
    Sakai, Yoshitada
    Hashiramoto, Akira
    JOURNAL OF IMMUNOLOGY RESEARCH, 2014, 2014
  • [43] Seasonal fluctuations of inflammatory cytokines in Rheumatoid arthritis Iraqi patients
    Abd, Reham Najim
    Mahmood, Majid Mohammed
    Albayati, Asaad F.
    PAKISTAN JOURNAL OF MEDICAL & HEALTH SCIENCES, 2021, 15 (04): : 1006 - 1008
  • [44] Seasonal Fluctuations of Inflammatory Cytokines in Rheumatoid Arthritis Iraqi Patients
    ABD, Reham Najim
    Mahmood, Majid Mohammed
    Albayati, Asaad F.
    JOURNAL OF RESEARCH IN MEDICAL AND DENTAL SCIENCE, 2021, 9 (08): : 334 - 338
  • [45] T cells in rheumatoid arthritis
    Cope, Andrew P.
    ARTHRITIS RESEARCH & THERAPY, 2008, 10 (Suppl 1)
  • [46] Pro- and anti-inflammatory cytokines in rheumatoid arthritis
    Isomäki, P
    Punnonen, J
    ANNALS OF MEDICINE, 1997, 29 (06) : 499 - 507
  • [47] Interactions between the inflammatory Cytokines of rheumatoid arthritis in osteoclastogenesis.
    O'Gradaigh, DM
    Compston, JE
    ARTHRITIS AND RHEUMATISM, 2002, 46 (09): : S201 - S201
  • [48] T cells in rheumatoid arthritis
    Andrew P Cope
    Arthritis Research & Therapy, 10
  • [49] In vitro elimination of autoreactive B cells from rheumatoid arthritis patients by universal chimeric antigen receptor T cells
    Zhang, Bo
    Wang, Yan
    Yuan, Yeshuang
    Sun, Jiaqi
    Liu, Lulu
    Huang, Dan
    Hu, Jin
    Wang, Min
    Li, Shengjie
    Song, Wei
    Chen, Hua
    Zhou, Demin
    Zhang, Xuan
    ANNALS OF THE RHEUMATIC DISEASES, 2021, 80 (02) : 176 - 184
  • [50] Targeting the T cell receptor in rheumatoid arthritis
    Kotzin, BL
    Kappler, J
    ARTHRITIS AND RHEUMATISM, 1998, 41 (11): : 1906 - 1910
12345