Immunotherapy of Rheumatoid Arthritis Targeting Inflammatory Cytokines and Autoreactive T Cells

被引：25
作者：
Chen, Guangjie [1 ]
机构：
[1] Shanghai Jiao Tong Univ, Sch Med, Inst Med Sci, Dept Immunol, Shanghai 200025, Peoples R China
来源：
ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS | 2010年 / 58卷 / 01期
关键词：
Rheumatoid arthritis; Immunotherapy; Inflammatory cytokines; Autoreactive T cells; Regulatory T cells; Th17; cells; PLACEBO-CONTROLLED TRIAL; NECROSIS-FACTOR-ALPHA; COLLAGEN-INDUCED ARTHRITIS; ANTI-INTERLEUKIN-6 RECEPTOR ANTIBODY; CONTROLLED CLINICAL-TRIAL; LONG-TERM SAFETY; PHASE-III TRIAL; DOUBLE-BLIND; TNF-ALPHA; RANDOMIZED-TRIAL;
D O I：
10.1007/s00005-009-0058-1
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Rheumatoid arthritis is a chronic disorder for which there is no known cure. Concentrating on specific elements of the abnormal immune response that characterizes the disease, scientists are reaching into biotechnology's bag of tricks to develop immunotherapeutic techniques. This paper will present some advances in the immunotherapy of rheumatoid arthritis targeting inflammatory cytokines and autoreactive T cells.
引用
收藏
页码：27 / 36
页数：10
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