Phosphorylation Of Tau by Cdk5 and Gsk3β is Modulated by Aberrant Glycosylation at A Site-Specific Manner

被引：0
|
作者：
Liu, F. [1 ]
Zaid, T. [1 ]
Iqbal, K. [1 ]
Grundke-Iqbal, I. [1 ]
Gong, C. X. [1 ]
机构：
[1] New York State Inst Basic Res Dev Disabil, Dept Neurochem, Staten Isl, NY 10314 USA
来源：
JOURNAL OF ALZHEIMERS DISEASE | 2002年 / 4卷 / 01期
关键词：
D O I：
暂无
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
19
引用
收藏
页码：49 / 50
页数：2
相关论文
共 50 条
  • [21] Age-dependent alterations in tau hyperphosphorylation, APP processing and inhibition of GSK3 mediated by Cdk5 activity
    Plattner, F
    Angelo, M
    Ris, L
    Strand, C
    Revesz, T
    Holton, JL
    Giese, KP
    NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, 2005, 31 (02) : 221 - 221
  • [22] Involvement of D1 dopamine receptor signaling in hyper-phosphorylation of the microtubule associated protein tau: A pivotal role for CDK5 and GSK3
    Le Bel, M.
    Cyr, M.
    MOVEMENT DISORDERS, 2008, 23 (01) : S86 - S87
  • [23] PKA modulates GSK-3β- and cdk5-catalyzed phosphorylation of tau in site- and kinase-specific manners
    Liu, Fei
    Liang, Zhihou
    Shi, Jianhua
    Yin, Dongmei
    El-Akkad, Ezzat
    Grundke-Iqbal, Inge
    Iqbal, Khalid
    Gong, Cheng-Xin
    FEBS LETTERS, 2006, 580 (26) : 6269 - 6274
  • [24] Phosphorylation of p35 and p39 by Cdk5 determines the subcellular location of the holokinase in a phosphorylation-site-specific manner
    Asada, Akiko
    Saito, Taro
    Hisanaga, Shin-ichi
    JOURNAL OF CELL SCIENCE, 2012, 125 (14) : 3421 - 3429
  • [25] CDK5 activator protein p25 preferentially binds and activates GSK3β
    Chow, Hei-Man
    Guo, Dong
    Zhou, Jie-Chao
    Zhang, Guan-Yun
    Li, Hui-Fang
    Herrup, Karl
    Zhang, Jie
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (45) : E4887 - E4895
  • [26] Pre-phosphorylated tau by PKA is a better substrate for GSK-3β, but not for cdk5
    Shi, J. H.
    Ding, S. H.
    Grundke-Iqbal, I.
    Iqbal, K.
    C-X, Gong
    Liu, F.
    JOURNAL OF NEUROCHEMISTRY, 2006, 98 : 17 - 17
  • [27] Curcumin Downregulates GSK3 and Cdk5 in Scopolamine-Induced Alzheimer's Disease Rats Abrogating Aβ40/42 and Tau Hyperphosphorylation
    Das, Tushar Kanti
    Jana, Piyali
    Chakrabarti, Swarup Kumar
    Hamid, Mas R. W. Abdul
    JOURNAL OF ALZHEIMERS DISEASE REPORTS, 2019, 3 (01) : 257 - 267
  • [28] Site-specific phosphorylation of synapsin I by mitogen-activated protein kinase and Cdk5 and its effects on physiological functions
    Matsubara, M
    Kusubata, M
    Ishiguro, K
    Uchida, T
    Titani, K
    Taniguchi, H
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (35) : 21108 - 21113
  • [29] Involvement of Cdk5/GSK3β/CRMP signaling in Sema3A-induced facilitation of axonal transport
    Hida, Tomonobu
    Takeuchi, Kan
    Usui, Hiroshi
    Goshima, Yoshio
    NEUROSCIENCE RESEARCH, 2008, 61 : S149 - S149
  • [30] Roscovitine, a CDK5 Inhibitor, Alleviates Sevoflurane-Induced Cognitive Dysfunction via Regulation Tau/GSK3β and ERK/PPARγ/CREB Signaling
    Liu, Jianhui
    Yang, Junjun
    Xu, Yinhua
    Guo, Gang
    Cai, Li
    Wu, Heng
    Zhao, Yanhong
    Zhang, Xiaoqing
    CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2017, 44 (02) : 423 - 435
12345