Cancer prevention in HIV-infected populations

被引：38
作者：
Goncalves, Priscila H. [1 ]
Montezuma-Rusca, Jairo M. [2 ]
Yarchoan, Robert [1 ]
Uldrick, Thomas S. [1 ]
机构：
[1] NCI, HIV & AIDS Malignancy Branch, NIH, Bethesda, MD 20892 USA
[2] NIAID, Immunoregulat Lab, NIH, Bldg 10, Bethesda, MD 20892 USA
来源：
SEMINARS IN ONCOLOGY | 2016年 / 43卷 / 01期
关键词：
HIV; Neoplasms; Kaposi sarcoma; AIDS-related lymphoma; HPV vaccines; HUMAN-IMMUNODEFICIENCY-VIRUS; HEPATITIS-C VIRUS; SARCOMA-ASSOCIATED HERPESVIRUS; HUMAN-PAPILLOMAVIRUS INFECTION; COMBINATION ANTIRETROVIRAL THERAPY; SQUAMOUS INTRAEPITHELIAL LESIONS; CARDIOVASCULAR-DISEASE EVENTS; AIDS-DEFINING MALIGNANCIES; NON-HODGKIN-LYMPHOMA; T-CELL RESPONSES;
D O I：
10.1053/j.seminoncol.2015.09.011
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
People living with human immunodeficiency virus (HIV) are living longer since the advent of effective combined antiretroviral therapy (cART). While cART substantially decreases the risk of developing some cancers, HIV-infected individuals remain at high risk for Kaposi sarcoma, lymphoma, and several solid tumors. Currently HIV-infected patients represent an aging group, and malignancies have become a leading cause of morbidity and mortality. Tailored cancer-prevention strategies are needed for this population. In this review we describe the etiologic agents and pathogenesis of common malignancies in the setting of HIV, as well as current evidence for cancer prevention strategies and screening programs. Published by Elsevier Inc.
引用
收藏
页码：173 / 188
页数：16
相关论文
共 234 条
  • [1] Reduced Lung-Cancer Mortality with Low-Dose Computed Tomographic Screening
    Aberle, Denise R.
    Adams, Amanda M.
    Berg, Christine D.
    Black, William C.
    Clapp, Jonathan D.
    Fagerstrom, Richard M.
    Gareen, Ilana F.
    Gatsonis, Constantine
    Marcus, Pamela M.
    Sicks, JoRean D.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2011, 365 (05) : 395 - 409
  • [2] Increased regression and decreased incidence of human papillomavirus-related cervical lesions among HIV-infected women on HAART
    Adler, David H.
    Kakinami, Lisa
    Modisenyane, Tebogo
    Tshabangu, Nkeko
    Mohapi, Lerato
    De Bruyn, Guy
    Martinson, Neil A.
    Omar, Tanvier
    [J]. AIDS, 2012, 26 (13) : 1645 - 1652
  • [3] Albini L, 2013, AIDS RES HUM RETROV, V29, P1097, DOI [10.1089/aid.2012.0321, 10.1089/AID.2012.0321]
  • [4] CC CKRS: A RANTES, MIP-1 alpha, MIP-1 beta receptor as a fusion cofactor for macrophage-tropic HIV-1
    Alkhatib, G
    Combadiere, C
    Broder, CC
    Feng, Y
    Kennedy, PE
    Murphy, PM
    Berger, EA
    [J]. SCIENCE, 1996, 272 (5270) : 1955 - 1958
  • [5] [Anonymous], 12 INT C MAL AIDS OT
  • [6] [Anonymous], 2014, European AIDS Clinical Society guidelines Version 7.1 November 2014
  • [7] [Anonymous], ANN ONCOL
  • [8] [Anonymous], EUR J PREV CARD 0416
  • [9] [Anonymous], ANN INTERN MED 2
  • [10] HIV-1 Tat enhances Kaposi sarcoma-associated herpesvirus (KSHV) infectivity
    Aoki, Y
    Tosato, G
    [J]. BLOOD, 2004, 104 (03) : 810 - 814
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