The scent of human diseases: a review on specific volatile organic compounds as diagnostic biomarkers

被引:83
|
作者
Buljubasic, Fanis [1 ]
Buchbauer, Gerhard [1 ]
机构
[1] Heidelberg Univ, Gen Hosp Mannheim, Dept Internal Med, Div Pulmonol, D-69115 Heidelberg, Germany
关键词
biomarker; VOCs; odour; disease diagnosis; e-nose; sniffer dogs; healthcare applications; review; SOLID-PHASE MICROEXTRACTION; OBSTRUCTIVE PULMONARY-DISEASE; EXHALED BREATH CONDENSATE; PROSTATE-CANCER PATIENTS; LUNG-CANCER; OXIDATIVE STRESS; PSEUDOMONAS-AERUGINOSA; ISOVALERIC ACIDEMIA; ELECTRONIC NOSE; INBORN ERROR;
D O I
10.1002/ffj.3219
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
The use of body odours, emitted in the form of volatile organic compounds (VOCs), has become the focus of scientific research in recent years. Diseases such as cancer, metabolic disorders, infections and some other diseases can change the components of daily VOCs, often leading to the production of disease-specific VOCs that might be used as diagnostic biomarkers if detected early enough. We summarize here scientific publications (2003-2013) related to the study of VOCs in human diseases. Copyright (c) 2014 John Wiley & Sons, Ltd.
引用
收藏
页码:5 / 25
页数:21
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