Comparative in vitro activities of carbapenem antimicrobial agents against 264 penicillin-resistant Streptococcus pneumoniae isolates from Korea

被引：5
作者：
Choi, Sang-Ho
Park, Su Jin
Jun, Jae-Bum
Lee, Sang-Rok
Jeon, Min-Hyuk
Kwon, Hyun-Hee
Kim, Seong Cherl
Kim, Mi-Na
Jeong, Jin-Yong
Woo, Jun Hee
Kim, Yang Soo [1 ]
机构：
[1] Univ Ulsan, Coll Med, Asan Med Ctr, Div Infect Dis, Seoul 138736, South Korea
[2] Univ Ulsan, Ctr Antimicrobial Resistance & Microbial Genet, Seoul 138736, South Korea
[3] Univ Ulsan, Coll Med, Dept Lab Med, Asan Med Ctr, Seoul 138736, South Korea
来源：
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2007年 / 58卷 / 01期
关键词：
Streptococcus pneumoniae; carbapenems; imipenem; meropenem; ertapenem; panipenem;
D O I：
10.1016/j.diagmicrobio.2006.11.017
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
We compared in vitro activities of carbapenems against 264 penicillin-resistant Streptococcus pneumoniae (PRSP) isolates. The MIC50/ MIC90 (mu g/mL) values of imipenem, meropenem, ertapenem, and panipenem were 1/1, 0.25/0.25, 0.25/0.5, and 0.125/0.25, respectively. The susceptibility rates to imipenem, meropenem, and ertapenern were 0%, 85.2%, and 99.6%, respectively. Compared with imipenem and meropenem, ertapenem and pampenem had better in vitro activities against PRSP. (c) 2007 Elsevier Inc. All rights reserved.
引用
收藏
页码：141 / 143
页数：3
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