Quantifying HIV for Monitoring Antiretroviral Therapy in Resource-Poor Settings

被引：56

作者：

Stevens, Wendy S. ^{[1
]}

Scott, Lesley E. ^{[1
]}

Crowe, Suzanne M. ^{[2
,3
]}

机构：

[1] Univ Witwatersrand, Dept Mol Med & Haematol, Johannesburg, South Africa

[2] Monash Univ, Dept Med, Melbourne, Vic 3004, Australia

[3] Monash Univ, Burnet Inst, Ctr Virol, Melbourne, Vic 3004, Australia

来源：

JOURNAL OF INFECTIOUS DISEASES | 2010年 / 201卷

基金：

美国国家卫生研究院;

关键词：

IMMUNODEFICIENCY-VIRUS TYPE-1; P24; ANTIGEN-ASSAY; T-CELL COUNT; REVERSE-TRANSCRIPTASE ACTIVITY; NUCLISENS EASYQ ASSAY; COBAS TAQMAN HIV-1; DRIED BLOOD SPOTS; HEPATITIS-C VIRUS; VIRAL LOAD ASSAYS; REAL-TIME PCR;

D O I：

10.1086/650392

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

There is increasing evidence to support the inability of CD4 cell count monitoring to predict virological failure in human immunodeficiency virus-infected individuals receiving antiretroviral therapy. There is renewed interest in improving access to viral load monitoring in resource-constrained regions to monitor adherence to treatment and to switch therapy. The field is rapidly changing as new technology platforms are made available for evaluation. This article presents an up to date summary of the assays available for viral load monitoring and suggests approaches for their implementation.

引用

页码：S16 / S26

页数：11

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