Antibacterial Hydrogels

被引：876
作者：
Li, Shuqiang [1 ]
Dong, Shujun [2 ,3 ]
Xu, Weiguo [2 ]
Tu, Shicheng [1 ]
Yan, Lesan [2 ]
Zhao, Changwen [2 ]
Ding, Jianxun [2 ]
Chen, Xuesi [2 ]
机构：
[1] Jilin Univ, Hosp 1, Dept Bone & Joint Surg, Changchun 130022, Jilin, Peoples R China
[2] Chinese Acad Sci, Changchun Inst Appl Chem, Key Lab Polymer Ecomat, Changchun 130022, Jilin, Peoples R China
[3] Jilin Univ, Sch & Hosp Stomatol, VIP Integrated Dept, Changchun 130021, Jilin, Peoples R China
来源：
ADVANCED SCIENCE | 2018年 / 5卷 / 05期
基金：
中国国家自然科学基金;
关键词：
antibacterial properties; biomedical applications; hydrogels; SELF-ASSEMBLING PEPTIDES; ANTIMICROBIAL PROPERTIES; NANOCOMPOSITE HYDROGELS; WOUND DRESSINGS; SILVER NANOPARTICLES; IN-VITRO; CONTROLLED-RELEASE; DELIVERY-SYSTEM; DRUG-RELEASE; THERMOSENSITIVE HYDROGEL;
D O I：
10.1002/advs.201700527
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Antibacterial materials are recognized as important biomaterials due to their effective inhibition of bacterial infections. Hydrogels are 3D polymer networks crosslinked by either physical interactions or covalent bonds. Currently, hydrogels with an antibacterial function are a main focus in biomedical research. Many advanced antibacterial hydrogels are developed, each possessing unique qualities, namely high water swellability, high oxygen permeability, improved biocompatibility, ease of loading and releasing drugs, and structural diversity. Here, an overview of the structures, performances, mechanisms of action, loading and release behaviors, and applications of various antibacterial hydrogel formulations is provided. Furthermore, the prospects in biomedical research and clinical applications are predicted.
引用
收藏
页数：17
相关论文
共 171 条
[1]   Antimicrobial activity of silver/starch/polyacrylamide nanocomposite [J].
Abdel-Halim, E. S. ;
Al-Deyab, Salem S. .
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2014, 68 :33-38
[2]   PEGylated gold nanorods as optical trackers for biomedical applications: an in vivo and in vitro comparative study [J].
Abdelrasoul, Gaser N. ;
Magrassi, Raffaella ;
Dante, Silvia ;
d'Amora, Marta ;
d'Abbusco, Marco Scotto ;
Pellegrino, Teresa ;
Diaspro, Alberto .
NANOTECHNOLOGY, 2016, 27 (25)
[3]   Comparative eco-toxicity of nanoscale TiO2, SiO2, and ZnO water suspensions [J].
Adams, Laura K. ;
Lyon, Delina Y. ;
Alvarez, Pedro J. J. .
WATER RESEARCH, 2006, 40 (19) :3527-3532
[4]  
[Anonymous], BMJ BRIT MED J
[5]   Next generation of antimicrobial peptides as molecular targeted medicines [J].
Aoki, Wataru ;
Kuroda, Kouichi ;
Ueda, Mitsuyoshi .
JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 2012, 114 (04) :365-370
[6]   Evaluation of chitosan nano dressing for wound healing: Characterization, in vitro and in vivo studies [J].
Archana, D. ;
Dutta, Joydeep ;
Dutta, P. K. .
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2013, 57 :193-203
[7]   Enzymatic Regulation of Self-Assembling Peptide A9K2 Nanostructures and Hydrogelation with Highly Selective Antibacterial Activities [J].
Bai, Jingkun ;
Chen, Cuixia ;
Wang, Jingxin ;
Zhang, Yu ;
Cox, Henry ;
Zhang, Jing ;
Wang, Yuming ;
Penny, Jeffrey ;
Waigh, Thomas ;
Lu, Jian R. ;
Xu, Hai .
ACS APPLIED MATERIALS & INTERFACES, 2016, 8 (24) :15093-15102
[8]   Magnetically mediated release of ciprofloxacin from polyvinyl alcohol based superparamagnetic nanocomposites [J].
Bajpai, A. K. ;
Gupta, Rashmi .
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2011, 22 (02) :357-369
[9]   A Peptide-Based Mechano-sensitive, Proteolytically Stable Hydrogel with Remarkable Antibacterial Properties [J].
Baral, Abhishek ;
Roy, Subhasish ;
Ghosh, Srabanti ;
Hermida-Merino, Daniel ;
Hamley, Ian W. ;
Banerjee, Arindam .
LANGMUIR, 2016, 32 (07) :1836-1845
[10]   MEDICAL HYDROGELS BASED ON BIOACTIVE COMPOUNDS. SYNTHESIS, PROPERTIES, AND POSSIBLE APPLICATION FOR PREPARING BACTERICIDAL MATERIALS [J].
Baranova, O. A. ;
Kuz'min, N. I. ;
Samsonova, T. I. ;
Rebetskaya, I. S. ;
Petrova, O. P. ;
Pakhomov, P. M. ;
Khizhnyak, S. D. ;
Komarov, P. V. ;
Ovchinnikov, M. M. .
FIBRE CHEMISTRY, 2011, 43 (01) :90-103
12345678910