Follicular Dendritic Cell Sarcoma

被引:66
作者
Chen, Tiffany [1 ]
Gopal, Purva [2 ]
机构
[1] Univ Texas Dallas, Southwestern Med Sch, 5323 Harry Hines Blvd, Dallas, TX 75390 USA
[2] Univ Texas Southwestern Med Ctr Dallas, Dept Pathol, Dallas, TX USA
关键词
EPSTEIN-BARR-VIRUS; OF-THE-LITERATURE; INFLAMMATORY PSEUDOTUMOR; CASTLEMANS-DISEASE; TUMOR; EXPRESSION; NEOPLASMS; CLUSTERIN; LYMPHOMA; SPLEEN;
D O I
10.5858/arpa.2016-0126-RS
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
Follicular dendritic cell sarcoma is a rare tumor that typically arises within lymph nodes but can also occur extranodally. It is important to have a high index of suspicion, so follicular dendritic cell sarcoma is included in the differential diagnosis of a spindle cell neoplasm in the appropriate clinical and morphologic settings. When included in the differential diagnosis, immunohistochemistry is generally sufficient to substantiate the diagnosis of follicular dendritic cell sarcoma. In this review, we discuss the clinicopathologic features of follicular dendritic cell sarcoma, recent molecular and cytogenetic findings, prognosis, and current approaches to treatment.
引用
收藏
页码:596 / 599
页数:4
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