Covalent Attachment of Polymersomes to Surfaces

被引：22

作者：

Domes, Stephanie ^{[1
]}

Filiz, Volkan ^{[1
]}

Nitsche, Jasmin ^{[1
]}

Froemsdorf, Andreas ^{[1
]}

Foerster, Stephan ^{[1
]}

机构：

[1] Univ Hamburg, Inst Phys Chem, D-20146 Hamburg, Germany

来源：

LANGMUIR | 2010年 / 26卷 / 10期

关键词：

BLOCK-COPOLYMERS; VESICLES; LIPOSOMES; MICELLES; ADHESION; DELIVERY;

D O I：

10.1021/la904175u

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We show that vesicles made of block copolymers with aldehyde end groups can be covalently attached to aminated and non-aminated, untreated glass surfaces. The attached vesicles were sufficiently stable to allow a detailed in of vesicle shapes by confocal laser scanning microscopy (CLSM) and A FM in aqueous solutions allowing reconstruction of 3D images of the vesicle structure. Covalently attached PCL-PEO, PLA-PEO, and PI-PEO block copolymer vesicles have different footprint areas and different shapes due to their differences in bilayer stiffness.

引用

页码：6927 / 6931

页数：5

共 22 条

[11] LIPOSOMES REVISITED [J].

LASIC, DD ;

PAPAHADJOPOULOS, D .

SCIENCE, 1995, 267 (5202) :1275-1276

[12] Preparation, stability, and in vitro performance of vesicles made with diblock copolymers [J].

Lee, JCM ;

Bermudez, H ;

Discher, BM ;

Sheehan, MA ;

Won, YY ;

Bates, FS ;

Discher, DE .

BIOTECHNOLOGY AND BIOENGINEERING, 2001, 73 (02) :135-145

[13] Gentle immobilization of nonionic polymersomes on solid substrates [J].

Li, Feng ;

Ketelaar, Tijs ;

Stuart, Martien A. Cohen ;

Sudholter, Ernst J. R. ;

Leermakers, Frans A. M. ;

Marcelis, Antonius T. M. .

LANGMUIR, 2008, 24 (01) :76-82

[14]

Lipowsky R., 1995, P521

[15]

RINGSDORF H, 1988, ANGEW CHEM, V100, P117

[16] A NOVEL REACTIVE POLYMERIC MICELLE WITH ALDEHYDE GROUPS ON ITS SURFACE [J].

SCHOLZ, C ;

IIJIMA, M ;

NAGASAKI, Y ;

KATAOKA, K .

MACROMOLECULES, 1995, 28 (21) :7295-7297

[17] Vesicle adsorption and lipid bilayer formation on glass studied by atomic force microscopy [J].

Schönherr, H ;

Johnson, JM ;

Lenz, P ;

Frank, CW ;

Boxer, SG .

LANGMUIR, 2004, 20 (26) :11600-11606

[18] Dess-Martin-Periodinane (DMP) [J].

Speicher, A ;

Bomm, V ;

Eicher, T .

JOURNAL FUR PRAKTISCHE CHEMIE-CHEMIKER-ZEITUNG, 1996, 338 (06) :588-590

[19] Mild oxidation of alcohols with o-iodoxybenzoic acid (IBX) in water/acetone mixture in the presence of β-cyclodextrin [J].

Surendra, K ;

Krishnaveni, NS ;

Reddy, MA ;

Nageswar, YVD ;

Rao, KR .

JOURNAL OF ORGANIC CHEMISTRY, 2003, 68 (05) :2058-2059

[20] Conjugation of arginine-glycine-aspartic acid peptides to poly(ethylene oxide)-b-poly(ε-caprolactone) micelles for enhanced intracellular drug delivery to metastatic tumor cells [J].

Xiong, Xiao-Bing ;

Mahmud, Abdullah ;

Uludag, Hasan ;

Lavasanifar, Afsaneh .

BIOMACROMOLECULES, 2007, 8 (03) :874-884

← 1 2 3 →